RAB8A anticorps (C-Term)

N° du produit ABIN3042554

Détail du produit anti-RAB8A anticorps

Antigène: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Épitope: AA 170-183, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB8A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Ras-related protein Rab-8A(RAB8A) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: KAKMDKKLEG NSPQ

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Ras-related protein Rab-8A(RAB8A) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: RAB8A, member RAS oncogene family
Protein Name: Ras-related protein Rab-8A

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human RAB8A(170-183aa KAKMDKKLEGNSPQ), identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur RAB8A

Antigène: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Autre désignation: RAB8A (RAB8A Produits)

Synonymes: anticorps rab8A, anticorps DDBDRAFT_0206521, anticorps DDBDRAFT_0214885, anticorps DDB_0206521, anticorps DDB_0214885, anticorps HSH2D, anticorps mel, anticorps rab8, anticorps c-mel, anticorps MEL, anticorps RAB8, anticorps zgc:162699, anticorps AA409338, anticorps Mel, anticorps Rab8, anticorps rab8A protein, anticorps Rab GTPase, anticorps RAB8A, member RAS oncogene family, anticorps RAB8A, member RAS oncogene family S homeolog, anticorps rab8A, anticorps RAB8A, anticorps rab8a, anticorps rab8a.S, anticorps Rab8a

Sujet: Ras-related protein Rab-8A is a protein that in humans is encoded by the RAB8A gene. It is mapped to 19p13.12. The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. RAB8A regulates cilia assembly by targeting and promoting fusion of vesicles near the ciliary membrane. This gene requires CEP290 for centrosome localization and that CEP290 regulates entry of RAB8A into the cilium during assembly of this organelle. RAB8A has been shown to interact with Optineurin and MAP4K2.

Synonyms: AA409338 antibody|MEL antibody|Mel transforming oncogene(derived from cell line NK14) RAB8 homolog antibody|Mel transforming oncogene(derived from cell line NK14) antibody|Mel transforming oncogene(RAB8 homolog) antibody|Mel transforming oncogene antibody|MGC124948 antibody|Oncogene c mel antibody|Oncogene c-mel antibody|RAB8 antibody|RAB8A antibody|RAB8A member RAS oncogene family antibody|Ras associated protein RAB8 antibody|Ras related protein Rab 8A antibody|Ras-related protein Rab-8A antibody

UniProt: P61006

Pathways: M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome