P-Cadherin anticorps (Middle Region)

N° du produit ABIN3042613

Détail du produit anti-P-Cadherin anticorps

Antigène: P-Cadherin (CDH3)

Épitope: AA 612-626, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P-Cadherin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Fonction: Rabbit IgG polyclonal antibody for Cadherin-3(CDH3) detection. Tested with WB, IHC-P, ICC in Human.

Séquence: QDTYDVHLSL SDHGN

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Cadherin-3(CDH3) detection. Tested with WB, IHC-P, ICC in Human.
Gene Name: cadherin 3, type 1, P-cadherin(placental)
Protein Name: Cadherin-3

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human P cadherin(612-626aa QDTYDVHLSLSDHGN), different from the mouse and rat sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur P-Cadherin

Antigène: P-Cadherin (CDH3)

Autre désignation: CDH3 (CDH3 Produits)

Synonymes: anticorps CDH3, anticorps Cadherin-3, anticorps AI385538, anticorps Cadp, anticorps Cdhp, anticorps P-cadherin, anticorps Pcad, anticorps CDHP, anticorps HJMD, anticorps PCAD, anticorps E-Cad, anticorps E-cadherin, anticorps EP-cadherin, anticorps XTCAD-1, anticorps c-cadherin, anticorps cadherin-1, anticorps cdh1, anticorps cdh1-b, anticorps cdh3, anticorps cdhc-A, anticorps cdhp, anticorps hjmd, anticorps l-cam, anticorps lcam, anticorps pcad, anticorps uvo, anticorps uvomorulin, anticorps xb-cad, anticorps xcdh1, anticorps CDH15, anticorps K-CAM, anticorps cadherin 3, anticorps cadherin 3 L homeolog, anticorps Cadherin-3, anticorps CDH3, anticorps Cdh3, anticorps cdh3.L, anticorps cdh-3

Sujet: Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

Synonyms: CADH3_HUMAN antibody|Cadherin 3 antibody|Cadherin 3 precursor antibody|Cadherin 3 type 1 antibody|Cadherin-3 antibody|Cadherin-3 precursor antibody|Cadp antibody|Calcium dependent adhesion protein placental antibody|Calcium-dependent adhesion protein placental antibody|CDH 3 antibody|CDH3 antibody|CDH3 protein antibody|CDHP antibody|HJMD antibody|P cadherin(placental) antibody|P-cadherin(placental) antibody|P-cadherin antibody|PCAD antibody|Placental cadherin antibody

UniProt: P22223