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LIF anticorps (C-Term)

LIF Reactivité: Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3042667
  • Antigène Voir toutes LIF Anticorps
    LIF (Leukemia Inhibitory Factor (LIF))
    Épitope
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 175-194, C-Term
    Reactivité
    • 47
    • 18
    • 11
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Souris, Rat
    Hôte
    • 44
    • 8
    • 2
    • 2
    • 2
    • 2
    Lapin
    Clonalité
    • 53
    • 7
    Polyclonal
    Conjugué
    • 42
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LIF est non-conjugé
    Application
    • 49
    • 25
    • 23
    • 15
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Fonction
    Rabbit IgG polyclonal antibody for Leukemia inhibitory factor(LIF) detection. Tested with WB in Mouse,Rat.
    Séquence
    DKEAFQRKKL GCQLLGTYKQ
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Leukemia inhibitory factor(LIF) detection. Tested with WB in Mouse,Rat.
    Gene Name: leukemia inhibitory factor
    Protein Name: Leukemia inhibitory factor(LIF)
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence at the C-terminus of mouse LIF(175-194aa DKEAFQRKKLGCQLLGTYKQ), identical to the related rat sequence.
    Isotype
    IgG
    Top Product
    Discover our top product LIF Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Thimerosal (Merthiolate), Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Date de péremption
    12 months
  • Zhang, Liu, Liu, Zhou, Song, Cao, An: "miR-182 aids in receptive endometrium development in dairy goats by down-regulating PTN expression." dans: PLoS ONE, Vol. 12, Issue 7, pp. e0179783, (2017) (PubMed).

    Dong, Sui, Huang, Wang, Hu, Xiong, Wang, Zhang: "MicroRNA-223-3p suppresses leukemia inhibitory factor expression and pinopodes formation during embryo implantation in mice." dans: American journal of translational research, Vol. 8, Issue 2, pp. 1155-63, (2016) (PubMed).

    Gui, Xiong, Yang, Li, Huang: "Effects of acupuncture on LIF and IL-12 in rats of implantation failure." dans: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 67, Issue 5, pp. 383-90, (2012) (PubMed).

    Xu, Sun, Li, Wu, Zhang, Feng: "Pinopodes, leukemia inhibitory factor, integrin-?3, and mucin-1 expression in the peri-implantation endometrium of women with unexplained recurrent pregnancy loss." dans: Fertility and sterility, Vol. 98, Issue 2, pp. 389-95, (2012) (PubMed).

    Li, Xu, Chen, Sun: "Effects of hydrosalpinx on pinopodes, leukaemia inhibitory factor, integrin beta3 and MUC1 expression in the peri-implantation endometrium." dans: European journal of obstetrics, gynecology, and reproductive biology, Vol. 151, Issue 2, pp. 171-5, (2010) (PubMed).

    Pei, Yu, Shi, Jia: "The effects of mifepristone on the expressions of osteopontin, interleukin-6 and leukemia inhibitory factor in the villi of early pregnant women." dans: Contraception, Vol. 82, Issue 4, pp. 379-84, (2010) (PubMed).

    Hu, Feng, Tang, Zhu, Lin, Yu: "LIF upregulates expression of NK-1R in NHBE cells." dans: Mediators of inflammation, Vol. 2006, Issue 5, pp. 84829, (2007) (PubMed).

  • Antigène
    LIF (Leukemia Inhibitory Factor (LIF))
    Autre désignation
    LIF (LIF Produits)
    Synonymes
    anticorps CDF, anticorps DIA, anticorps HILDA, anticorps MLPLI, anticorps LIF, interleukin 6 family cytokine, anticorps leukemia inhibitory factor, anticorps LIF, anticorps Lif
    Sujet
    LIF is a pleiotropic cytokine produced at the maternal-fetal interface which has been shown to play an essential role in implantation in mice. LIF is produced in high amounts by the human endometrium and the trophoblast itself, and LIF receptors are present on cytotrophoblast cells. LIF could, thus, play a role in modulating HLA-G production and immune tolerance at the maternal-fetal interface. The gene maps to 22q11-q12.2, between the Philadelphia translocation BCR gene and the breakpoint of the translocation in cell line GM2324 at 22q12.2.

    Synonyms: CDF antibody|Cholinergic Differentiation Factor antibody|D factor antibody|DIA antibody|Differentiation inducing factor antibody|differentiation inhibitory activity antibody|Differentiation stimulating factor antibody|Differentiation-stimulating factor antibody|Emfilermin antibody|Hepatocyte stimulating factor III antibody|HILDA antibody|Human interleukin in DA cells antibody|Leukemia inhibitory factor antibody|LIF antibody|Lif antibody|LIF_HUMAN antibody|Melanoma derived LPL inhibitor antibody|Melanoma-derived LPL inhibitor antibody|MLPLI antibody
    UniProt
    P09056
    Pathways
    Signalistation JAK/STAT, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding
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