CTH anticorps (AA 181-398)

N° du produit ABIN3042770

Détail du produit anti-CTH anticorps

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Épitope: AA 181-398

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTH est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Cystathionine gamma-lyase(CTH) detection. Tested with WB in Human,Mouse,Rat.

Réactivité croisée (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Cystathionine gamma-lyase(CTH) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: cystathionase (cystathionine gamma-lyase)
Protein Name: Cystathionine gamma-lyase

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Cystathionase recombinant protein (Position: D181-H398). Human Cystathionase shares 85.8% amino acid (aa) sequence identity with both mouse and rat Cystathionase.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-CTH (ABIN3042770)

Liu, Li, Liang, Li, Jiang, Chu, Yang: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." dans: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).

Qi, Zhao, Li, Shao, Wang, Sui, Yu, Shao, Gui, Li, Jia, Jiang, Li, Zhang, Wang, Wang: "High C-X-C motif chemokine 5 expression is associated with malignant phenotypes of prostate cancer cells via autocrine and paracrine pathways." dans: International journal of oncology, Vol. 53, Issue 1, pp. 358-370, (2018) (PubMed).

Shi, Guo, Shi, Yu, Song, Li: "Caffeic Acid Phenethyl Ester inhibit Hepatic Fibrosis by Nitric Oxide Synthase and Cystathionine Gamma-Lyase in Rats." dans: Medical science monitor : international medical journal of experimental and clinical research, Vol. 21, pp. 2774-80, (2016) (PubMed).

Chen, Wang, Li, Jiang, Lu, Zhou: "Heme Oxygenase-1 Promotes Delayed Wound Healing in Diabetic Rats." dans: Journal of diabetes research, Vol. 2016, pp. 9726503, (2016) (PubMed).

Guo, Duan, Wang, Zhou, Li, Sun: "Endogenous carbon monoxide downregulates hepatic cystathionine-γ-lyase in rats with liver cirrhosis." dans: Experimental and therapeutic medicine, Vol. 10, Issue 6, pp. 2039-2046, (2015) (PubMed).

Détails sur CTH

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Autre désignation: CTH (CTH Produits)

Synonymes: anticorps DYT17, anticorps DYT18, anticorps DYT9, anticorps EIG12, anticorps GLUT, anticorps GLUT1, anticorps GLUT1DS, anticorps HTLVR, anticorps PED, anticorps wu:fb48e03, anticorps wu:fb58d08, anticorps zgc:66001, anticorps zgc:85785, anticorps CTH, anticorps 0610010I13Rik, anticorps AI314617, anticorps BC019483, anticorps CSE, anticorps Cys3, anticorps cysA, anticorps SCQ11.03c, anticorps DDBDRAFT_0190313, anticorps DDBDRAFT_0191318, anticorps DDB_0190313, anticorps DDB_0191318, anticorps H, anticorps MGC75946, anticorps cystathionine gamma-lyase, anticorps solute carrier family 2 member 1, anticorps cystathionase (cystathionine gamma-lyase), anticorps cystathionine gamma-lyase L homeolog, anticorps CTH, anticorps SLC2A1, anticorps cth, anticorps Cth, anticorps SCO3920, anticorps mlr1566, anticorps TA_RS00415, anticorps MAP_RS15640, anticorps SPO3344, anticorps CNN01730, anticorps Mmcs_1928, anticorps RHA1_RS31820, anticorps HNE_1212, anticorps MAV_3867, anticorps MSMEG_2394, anticorps Mvan_2142, anticorps SACE_6136, anticorps Mflv_4220, anticorps cysA, anticorps cth.L

Sujet: Cystathionine gamma-lyase (or cystathionase) is an enzyme which breaks down cystathionine into cysteine and α-ketobutyrate. The International Radiation Hybrid Mapping Consortium mapped the CTH gene to chromosome 1. The CTH gene had earlier been assigned to chromosome 16 by study of somatic cell hybrids. It is demonstrated that hydrogen sulfide (H2S) is physiologically generated by CTH.

Synonyms: CGL_HUMAN antibody|CTH antibody|cystathionase (cystathionine gamma-lyase) antibody| Cystathionine gamma lyase antibody|Cystathionine gamma-lyase antibody|Cysteine desulfhydrase antibody|Gamma cystathionase antibody|Gamma-cystathionase antibody|Homoserine deaminase antibody|Homoserine dehydratase antibody|MGC9471 antibody

ID gène: 10664

UniProt: P32929

Pathways: ER-Nucleus Signaling, L'effet Warburg