PFN2 anticorps (C-Term)

N° du produit ABIN3042861

Détail du produit anti-PFN2 anticorps

Antigène: PFN2 (Profilin 2 (PFN2))

Épitope: AA 125-140, C-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFN2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Profilin-2(PFN2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: NKKAYSMAKY LRDSGF

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Profilin-2(PFN2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: profilin 2
Protein Name: Profilin-2

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Profilin 2(125-140aa NKKAYSMAKYLRDSGF), identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PFN2

Antigène: PFN2 (Profilin 2 (PFN2))

Autre désignation: PFN2 (PFN2 Produits)

Synonymes: anticorps D3S1319E, anticorps PFL, anticorps Pfn, anticorps Profilin2, anticorps XProfilin2, anticorps PFN2, anticorps PRO2, anticorps Profilin-2, anticorps pfl, anticorps d3s1319e, anticorps profilin-2, anticorps F17A13.170, anticorps F17A13_170, anticorps PRF2, anticorps PROFILIN, anticorps PROFILIN 2, anticorps profilin 2, anticorps wu:fb01g08, anticorps wu:fb54f09, anticorps wu:fd58f06, anticorps profilin 2, anticorps profilin 2 L homeolog, anticorps profilin homolog 2, anticorps Profilin-2, anticorps PFN2, anticorps Pfn2, anticorps pfn2.L, anticorps prf2, anticorps pfn2, anticorps pfn-2

Sujet: Profilin-2, also called PFN2, is a protein that in humans is encoded by the PFN2 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. This gene is mapped to 3q25.1. It is though to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. It binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

Synonyms: D3S1319E antibody|PFL antibody|PFN 2 antibody|PFN2 antibody|PROF2_HUMAN antibody|Profilin II antibody|Profilin-2 antibody|Profilin2 antibody|ProfilinII antibody

UniProt: P35080

Pathways: Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis