TOLLIP anticorps (C-Term)
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- Antigène Voir toutes TOLLIP Anticorps
- TOLLIP (Toll Interacting Protein (TOLLIP))
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Épitope
- AA 224-243, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TOLLIP est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- Rabbit IgG polyclonal antibody for Toll-interacting protein(TOLLIP) detection. Tested with WB, IHC-P in Human.
- Séquence
- NAQPRCSEED LKAIQDMFPN
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Toll-interacting protein(TOLLIP) detection. Tested with WB, IHC-P in Human.
Gene Name: toll interacting protein
Protein Name: Toll-interacting protein - Purification
- Immunogen affinity purified.
- Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminus of human Tollip(224-243aa NAQPRCSEEDLKAIQDMFPN).
- Isotype
- IgG
- Top Product
- Discover our top product TOLLIP Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for TOLLIP is approximately 0.5 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Agent conservateur
- Thimerosal (Merthiolate), Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Date de péremption
- 12 months
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Xuebijing exerts protective effects on lung permeability leakage and lung injury by upregulating Toll-interacting protein expression in rats with sepsis." dans: International journal of molecular medicine, Vol. 34, Issue 6, pp. 1492-504, (2014) (PubMed).
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Xuebijing exerts protective effects on lung permeability leakage and lung injury by upregulating Toll-interacting protein expression in rats with sepsis." dans: International journal of molecular medicine, Vol. 34, Issue 6, pp. 1492-504, (2014) (PubMed).
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- Antigène
- TOLLIP (Toll Interacting Protein (TOLLIP))
- Autre désignation
- TOLLIP (TOLLIP Produits)
- Synonymes
- anticorps IL-1RAcPIP, anticorps 4930403G24Rik, anticorps 4931428G15Rik, anticorps fk22a02, anticorps im:7145391, anticorps wu:fk22a02, anticorps zgc:76985, anticorps TOLLIP, anticorps GB17961, anticorps tollip, anticorps tollip1, anticorps tollipa, anticorps TOLIP, anticorps toll interacting protein, anticorps toll-interacting protein, anticorps toll-interacting protein-like, anticorps toll interacting protein L homeolog, anticorps toll interacting protein S homeolog, anticorps Toll-interleukine I receptor interacting protein I, anticorps TOLLIP, anticorps Tollip, anticorps tollip, anticorps LOC552034, anticorps LOC100169858, anticorps tollip.L, anticorps tollip.S, anticorps LOC100136122
- Sujet
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TOLLIP(TOLL-Interacting Protein), is an inhibitory adaptor protein that in humans is encoded by the TOLLIP gene. Lo et al.(2009) stated that the TOLLIP gene maps to chromosome 11. The mouse gene maps to chromosome 7. By Western blot analysis of embryonic kidney cells, Burns et al.(2000) confirmed the binding of TOLLIP to IL1RAP, to a complex of IL1RAP-IL1R1, and to IL18R. Burns et al.(2000) proposed that IL1B stimulation induces aggregation of IL1Rs, recruitment of MYD88 followed by TOLLIP-IRAK complexes, and the phosphorylation of IRAK by MYD88. This leads to the dissociation of TOLLIP from IRAK, which can then transmit the IL1-induced signals.
Synonyms: Adapter protein antibody|FLJ33531 antibody|IL 1RAcPIP antibody|IL1RAcPIP antibody|TOLIP antibody|TOLIP_HUMAN antibody|Toll interacting protein antibody|Toll-interacting protein antibody|tollip antibody - UniProt
- Q9H0E2
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