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CD163 anticorps (C-Term)

CD163 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3043012
  • Antigène Voir toutes CD163 Anticorps
    CD163
    Épitope
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    AA 1092-1109, C-Term
    Reactivité
    • 136
    • 47
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    Humain
    Hôte
    • 108
    • 53
    • 1
    Lapin
    Clonalité
    • 95
    • 66
    • 1
    Polyclonal
    Conjugué
    • 51
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    Cet anticorp CD163 est non-conjugé
    Application
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    Western Blotting (WB)
    Fonction
    Rabbit IgG polyclonal antibody for Scavenger receptor cysteine-rich type 1 protein M130(CD163) detection. Tested with WB in Human.
    Séquence
    HQIQYREMNS CLNADDLD
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Scavenger receptor cysteine-rich type 1 protein M130(CD163) detection. Tested with WB in Human.
    Gene Name: CD163 Molecule
    Protein Name: Scavenger receptor cysteine-rich type 1 protein M130
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence at the C-terminus of human CD163(1092-1109aa HQIQYREMNSCLNADDLD).
    Isotype
    IgG
    Top Product
    Discover our top product CD163 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for CD163 is approximately 2.5 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Thimerosal (Merthiolate), Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Date de péremption
    12 months
  • Liu, Xiao, Liu, Li, Zhou, Xian, Wang, Zhang, Wang, Ho, Zhuang: "SIV Infection Impairs the Central Nervous System in Chinese Rhesus Macaques." dans: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, Vol. 11, Issue 3, pp. 592-600, (2017) (PubMed).

    Huang, Chen, Wang, Wang, Ning, He, Hu, Yuan, Li, Wang, Liu, Chen, Ren, Sun: "Detecting cell-in-cell structures in human tumor samples by E-cadherin/CD68/CD45 triple staining." dans: Oncotarget, Vol. 6, Issue 24, pp. 20278-87, (2016) (PubMed).

  • Antigène
    CD163
    Autre désignation
    CD163 (CD163 Produits)
    Synonymes
    anticorps DMBT1, anticorps CD163, anticorps CD163v2, anticorps CD163v3, anticorps M130, anticorps MM130, anticorps deleted in malignant brain tumors 1 protein-like, anticorps CD163 molecule, anticorps CD163 antigen, anticorps LOC426820, anticorps CD163, anticorps Cd163
    Sujet
    CD163(Cluster of Differentiation 163) also known as HEMOGLOBIN SCAVENGER RECEPTOR, is a human protein encoded by the CD163 gene. The receptor belongs to the scavenger receptor cysteine rich family type B and consists of an 1048 amino acid residues extracellular domain, a single transmembrane segment and a cytoplasmic tail with several splice variants. CD163 is a scavenger receptorfor the hemoglobin-haptoglobincomplex. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, Stover et al.(2000) mapped the CD163 gene to chromosome 12p13.3. Specific CD163-mediated endocytosis of haptoglobin-hemoglobin complexes was measurable in cells transfected with CD163 cDNA and in CD163-expressing myelomonocytic lymphoma cells.CD163 expression in monocytes promoted bacteria-induced proinflammatory cytokine production that could be blocked by anti-CD163 antibodies. Cells expressing human CD163 and recombinant protein containing the extracellular domain of CD163 supported adhesion of erythroblastic cells.

    Synonyms: C163A_HUMAN antibody|CD 163 antibody|CD163 antibody|CD163 antigen antibody|CD163 Molecule antibody|Hemoglobin Scavenger Receptor antibody|M130 antibody|M130 antigen precursor antibody|Macrophage associated antigen antibody|MM130 antibody|OTTHUMP00000238617 antibody|OTTHUMP00000238618 antibody|OTTHUMP00000238619 antibody|OTTHUMP00000238620 antibody|Scavenger receptor cysteine rich type 1 protein M130 antibody|sCD163 antibody|Soluble CD163 antibody
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