HMGB4 anticorps (N-Term)

N° du produit ABIN3043021

Détail du produit anti-HMGB4 anticorps

Antigène: HMGB4 (High Mobility Group Box 4 (HMGB4))

Épitope: AA 24-41, N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMGB4 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for High mobility group protein B4(HMGB4) detection. Tested with WB in Human,Mouse,Rat.

Séquence: RNKFKEQQPN TYVGFKEF

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for High mobility group protein B4(HMGB4) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: high mobility group box 4
Protein Name: High mobility group protein B4

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human HMGB4(24-41aa RNKFKEQQPNTYVGFKEF), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-HMGB4 (ABIN3043021)

Rouhiainen, Zhao, Vanttola, Qian, Kulesskiy, Kuja-Panula, Gransalke, Grönholm, Unni, Meistrich, Tian, Auvinen, Rauvala: "HMGB4 is expressed by neuronal cells and affects the expression of genes involved in neural differentiation." dans: Scientific reports, Vol. 6, pp. 32960, (2018) (PubMed).

Zhao, Xue, Wang: "HMGB1, TGF-β and NF-κB are associated with chronic allograft nephropathy." dans: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 6138-6146, (2017) (PubMed).

Détails sur HMGB4

Antigène: HMGB4 (High Mobility Group Box 4 (HMGB4))

Autre désignation: HMGB4 (HMGB4 Produits)

Synonymes: anticorps HMGB4, anticorps dJ1007G16.5, anticorps 1700001F22Rik, anticorps AI326135, anticorps high mobility group box 4, anticorps high-mobility group box 4, anticorps HMGB4, anticorps Hmgb4

Sujet: HMGB4 is HMG2 like, isoform 2, high-mobility group box 4. This gene can be found on Chromosome 1. HMGB4 contains two HMG-box regions, which is found in a variety of eukaryotic chromosomal proteins and transcription. HMGB proteins are phosphorylated to various extents reveals that the existence of differentially modified forms increases the number of distinct HMGB protein variants in plant chromatin that may be adapted to certain functions.

Synonyms: High mobility group box 4 antibody|High mobility group protein B4 antibody|HMG2 like antibody