SRSF1 anticorps (N-Term)

N° du produit ABIN3043296

Détail du produit anti-SRSF1 anticorps

Antigène: SRSF1 (serine/arginine-Rich Splicing Factor 1 (SRSF1))

Épitope: AA 6-33, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRSF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Serine/arginine-rich splicing factor 1(SRSF1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: VIRGPAGNND CRIYVGNLPP DIRTKDIE

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Serine/arginine-rich splicing factor 1(SRSF1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: serine/arginine-rich splicing factor 1
Protein Name: Serine/arginine-rich splicing factor 1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of Human SF2(6-33aa VIRGPAGNNDCRIYVGNLPPDIRTKDIE), identical to the related mouse sequence.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat , The detection limit for SF2 is approximately 0.2 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur SRSF1

Antigène: SRSF1 (serine/arginine-Rich Splicing Factor 1 (SRSF1))

Autre désignation: SRSF1 (SRSF1 Produits)

Synonymes: anticorps ASF, anticorps SF2, anticorps SF2p33, anticorps SFRS1, anticorps SRp30a, anticorps 1110054N12Rik, anticorps 5730507C05Rik, anticorps 6330415C05Rik, anticorps AI482334, anticorps AW491331, anticorps Asf, anticorps Sf2, anticorps Sfrs1, anticorps DKFZp469K2419, anticorps sfrs1, anticorps sfrs1b, anticorps wu:fb80g05, anticorps zgc:111894, anticorps zgc:65898, anticorps zgc:76897, anticorps asf, anticorps sf2, anticorps sf2p33, anticorps srp30a, anticorps sfrs1a, anticorps sfrs1l, anticorps wu:fb52g10, anticorps wu:fb97g12, anticorps zgc:66146, anticorps serine and arginine rich splicing factor 1, anticorps serine/arginine-rich splicing factor 1, anticorps serine/arginine-rich splicing factor 1b, anticorps serine/arginine-rich splicing factor 1 L homeolog, anticorps serine/arginine-rich splicing factor 1a, anticorps SRSF1, anticorps Srsf1, anticorps srsf1b, anticorps srsf1.L, anticorps srsf1a

Sujet: SF2, also known as Serine/arginine-rich splicing factor 1 (SRSF1), is a protein that in humans is encoded by the SFRS1 gene. This gene encodes a member of the arginine/serine-rich splicing factor protein family. There is a pseudogene of this gene on chromosome 13. The encoded protein can either activate or repress splicing, depending on its phosphorylation state and its interaction partners. Multiple transcript variants have been found for this gene. ASF/SF2 is necessary for all splicing reactions to occur, and influences splice site selection in a concentration-dependent manner, resulting in alternative splicing.

Synonyms: Alternative splicing factor 1 antibody|Alternative-splicing factor 1 antibody| arginine/serine-rich 1 antibody|ASF 1 antibody|ASF antibody|ASF-1 antibody|ASF1 antibody|FLJ53078 antibody|MGC5228 antibody|P33 subunit antibody|Pre mRNA splicing factor SF2 P33 subunit antibody|pre-mRNA-splicing factor SF2 antibody|Serine/arginine-rich splicing factor 1 antibody|SF2 antibody|SF2P33 antibody|SFRS1 antibody|Splicing factor 2 alternate splicing factor antibody|Splicing factor 2 antibody|Splicing factor antibody|Splicing factor arginine/serine rich 1 antibody|SR Splicing factor 1 antibody|SRp30a antibody|srsf1 antibody|SRSF1_HUMAN antibody

ID gène: 6426

UniProt: Q07955

Pathways: Ribonucleoprotein Complex Subunit Organization