Cyclin A1 anticorps (AA 64-263)

N° du produit ABIN3043480

Détail du produit anti-Cyclin A1 anticorps

Antigène: Cyclin A1 (CCNA1)

Épitope: AA 64-263

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin A1 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Cyclin-A1(CCNA1) detection. Tested with WB in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Cyclin-A1(CCNA1) detection. Tested with WB in Human.
Gene Name: cyclin A1
Protein Name: Cyclin-A1

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Cyclin A1 recombinant protein (Position: D64-E263). Human Cyclin A1 shares 78.5% and 79.5% amino acid (aa) sequence identity with mouse and rat Cyclin A1, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-Cyclin A1 (ABIN3043480)

Zeng, Ma, Chen, Qiu, Wu, Ling, Zeng: "Autocrine fibronectin from differentiating mesenchymal stem cells induces the neurite elongation in vitro and promotes nerve fiber regeneration in transected spinal cord injury." dans: Journal of biomedical materials research. Part A, Vol. 104, Issue 8, pp. 1902-11, (2017) (PubMed).

Yuan, Zheng, Li, Xiang, Gao, Ran, Sun, Huang, Xie, Du, Xiao: "Overexpression of miR-30a in lung adenocarcinoma A549 cell line inhibits migration and invasion via targeting EYA2." dans: Acta biochimica et biophysica Sinica, Vol. 48, Issue 3, pp. 220-8, (2016) (PubMed).

Détails sur Cyclin A1

Antigène: Cyclin A1 (CCNA1)

Autre désignation: CCNA1 (CCNA1 Produits)

Synonymes: anticorps fd14f08, anticorps wu:fd14f08, anticorps wu:fi20d12, anticorps zgc:111869, anticorps MGC81965, anticorps cyclin-A1, anticorps CCNA1, anticorps MGC132235, anticorps cyclin-A1-2, anticorps Cyclin-A1, anticorps ccna1, anticorps cyclin A1, anticorps cyclin A1 L homeolog, anticorps CYCLIN A1;2, anticorps cyclin A1 S homeolog, anticorps CCNA1, anticorps ccna1, anticorps ccna1.L, anticorps CYCA1;2, anticorps Ccna1, anticorps ccna1.S

Sujet: Cyclin-A1 is a protein that in humans is encoded by the CCNA1 gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. Also this cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: CCN A1 antibody|CCNA 1 antibody|CCNA1 antibody|CCNA1_HUMAN antibody|Cyclin-A1 antibody| CyclinA1 antibody|G2/mitotic specific cyclin A1 antibody|MGC132235 antibody|MGC159139 antibody

ID gène: 8900

UniProt: P78396

Pathways: Apoptose, Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA