ABI1 anticorps (N-Term)

N° du produit ABIN3043515

Détail du produit anti-ABI1 anticorps

Antigène: ABI1 (Abl-Interactor 1 (ABI1))

Épitope: AA 151-175, N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABI1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Abl interactor 1(ABI1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: HGVKWLKAKH GNNQPARTGT LSRTN

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Abl interactor 1(ABI1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: abl-interactor 1
Protein Name: Abl interactor 1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human ABI1 (151-175aa HGVKWLKAKHGNNQPARTGTLSRTN), identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for ABI1 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human , Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-ABI1 (ABIN3043515)

Cui, Yu, Dong, Chen, Zhang, Liu: "Downregulation of ABI1 expression affects the progression and prognosis of human gastric carcinoma." dans: Medical oncology (Northwood, London, England), Vol. 27, Issue 3, pp. 632-9, (2010) (PubMed).

Détails sur ABI1

Antigène: ABI1 (Abl-Interactor 1 (ABI1))

Autre désignation: ABI1 (ABI1 Produits)

Synonymes: anticorps ABI-1, anticorps ABLBP4, anticorps E3B1, anticorps NAP1BP, anticorps SSH3BP, anticorps SSH3BP1, anticorps NAP1, anticorps Ssh3bp1, anticorps E3b1, anticorps abi1, anticorps wu:fc66g09, anticorps wu:fk56a10, anticorps zgc:73174, anticorps MGC84356, anticorps ABI1, anticorps abi-1, anticorps e3b1, anticorps nap1bp, anticorps ssh3bp, anticorps ssh3bp1, anticorps wu:fe48a10, anticorps zgc:153534, anticorps DKFZp469P1319, anticorps abl interactor 1, anticorps abl-interactor 1, anticorps abl-interactor 1a, anticorps abl interactor 1 S homeolog, anticorps abl-interactor 1b, anticorps Abl-interactor 1, anticorps Abl interactor 1, anticorps ABI1, anticorps Abi1, anticorps abi1a, anticorps abi1.S, anticorps abi1, anticorps abi1b, anticorps Bm1_44660, anticorps LOAG_04356

Sujet: SSH3BP1 is also known as ABI1. ABI1 is a human homolog of mouse Abl-interactor-1 (Abi1), mapped on 10p11.2. ABI1 participates in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor (GEF) activities. It dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA, but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins. ABI1 plays a role in the leukemogenesis by translocating to MLL.

Synonyms: Abelson interactor 1 antibody|ABI 1 antibody|Abi-1 antibody|ABI1 antibody|ABI1_HUMAN antibody|Abl binding protein 4 antibody|Abl interactor 1 antibody|Abl interactor protein 1 antibody|Abl interactor protein 1 long antibody|Abl-binding protein 4 antibody|AblBP4 antibody|Ablphilin 1 antibody|E3B1 antibody|Eps8 binding protein antibody|Eps8 SH3 domain binding protein antibody|Eps8 SH3 domain-binding protein antibody|Eps8-binding protein antibody|Hssh3bp1 antibody|Interactor protein AblBP4 antibody|NAP1 antibody|Nap1 binding protein antibody|Nap1-binding protein antibody|NAP1BP antibody|Spectrin SH3 domain binding protein 1 antibody|Spectrin SH3 domain-binding protein 1 antibody|SSH3BP antibody

ID gène: 10006

Pathways: Signalisation RTK, Response to Water Deprivation, ER-Nucleus Signaling