DLG1 anticorps (AA 1-165)

N° du produit ABIN3043562

Détail du produit anti-DLG1 anticorps

Antigène: DLG1 (Discs, Large Homolog 1 (DLG1))

Épitope: AA 1-165

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLG1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Disks large homolog 1(DLG1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Disks large homolog 1(DLG1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: discs, large homolog 1 (Drosophila)
Protein Name: Disks large homolog 1

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SAP97 recombinant protein (Position: M1-A165). Human SAP97 shares 89.7% and 84.2% amino acid (aa) sequence identity with mouse and rat SAP97, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur DLG1

Antigène: DLG1 (Discs, Large Homolog 1 (DLG1))

Autre désignation: DLG1 (DLG1 Produits)

Synonymes: anticorps DLG1, anticorps Dlgh1, anticorps SAP97, anticorps B130052P05Rik, anticorps E-dlg/SAP97, anticorps SAP-97, anticorps mKIAA4187, anticorps DLGH1, anticorps dJ1061C18.1.1, anticorps hdlg, anticorps discs large MAGUK scaffold protein 1, anticorps discs, large homolog 1 (Drosophila), anticorps DLG1, anticorps Dlg1

Sujet: Disks large homolog 1 (DLG1), also known as synapse-associated protein 97 or SAP97, is a protein that in humans is encoded by the SAP97 gene. SAP97 is expressed throughout the body in epithelial cells, including the kidney and brain. There is some evidence that SAP97 regulates cell-to-cell adhesion during cell death, and may interact with HPV. In the brain, SAP97's function is involved in the trafficking of transmembrane receptors from the ER to the plasma membrane. SAP97's function has been investigated by reducing its expression by knockout or increasing its expression heterologously. Mice in which the SAP97 gene has been knocked out die perinatally, have a cleft palate, and deficiencies in renal function. Overexpression of SAP97 in mammalian neurons leads to increased synaptic strength.

Synonyms: Discs large homolog 1 antibody|discs large, Drosophila, homolog of, 1 antibody|discs, large homolog 1 (Drosophila) antibody|Disks large homolog 1 antibody|dJ1061C18.1.1 antibody| DKFZp761P0818 antibody|DKFZp781B0426 antibody|DLG 1 antibody|DLG1 antibody|DLG1_HUMAN antibody|DLGH 1 antibody|DLGH1 antibody|HDLG antibody|Presynaptic protein SAP97 antibody| SAP 97 antibody|SAP-97 antibody|SAP97 antibody|Synapse associated protein 97 antibody| Synapse-associated protein 97 antibody

ID gène: 1739

UniProt: Q12959

Pathways: Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response