NRIP1 anticorps (N-Term)

N° du produit ABIN3043581

Détail du produit anti-NRIP1 anticorps

Antigène: NRIP1 (Nuclear Receptor Interacting Protein 1 (NRIP1))

Épitope: AA 273-306, N-Term

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NRIP1 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Nuclear receptor-interacting protein 1(NRIP1) detection. Tested with WB in Human,Mouse,Rat.

Séquence: EAHLQQYSRE HALKTQNANQ AASERLAAMA RLQE

Réactivité croisée (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Nuclear receptor-interacting protein 1(NRIP1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: nuclear receptor interacting protein 1
Protein Name: Nuclear receptor-interacting protein 1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human RIP140 (273-306aa EAHLQQYSREHALKTQNANQAASERLAAMARLQE), different from the related mouse sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur NRIP1

Antigène: NRIP1 (Nuclear Receptor Interacting Protein 1 (NRIP1))

Autre désignation: NRIP1 (NRIP1 Produits)

Synonymes: anticorps MGC68665, anticorps NRIP1, anticorps RIP140, anticorps 6030458L20Rik, anticorps 8430438I05Rik, anticorps 9630050P12, anticorps AA959574, anticorps AW456757, anticorps nuclear receptor interacting protein 1 S homeolog, anticorps nuclear receptor interacting protein 1, anticorps circumsporozoite protein, anticorps nrip1.S, anticorps NRIP1, anticorps nrip1, anticorps Nrip1, anticorps LOC100627733

Sujet: Nuclear receptor-interacting protein 1 (NRIP1), also known as receptor-interacting protein 140 (RIP140), is a protein that in humans is encoded by the NRIP1 gene. It is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein is a key regulator which modulates transcriptional activity of a variety of transcription factors, including the estrogen receptor. RIP140 has an important role in regulating lipid and glucose metabolism, and regulates gene expression in metabolic tissues including heart, skeletal muscle, and liver. A major role for RIP140 in adipose tissue is to block the expression of genes involved in energy dissipation and mitochondrial uncoupling, including uncoupling protein 1 and carnitine palmitoyltransferase 1b.

Synonyms: NRIP 1 antibody|NRIP1 antibody|NRIP1_HUMAN antibody|Nuclear factor RIP 140 antibody|Nuclear factor RIP140 antibody|Nuclear receptor interacting protein 1 antibody|Nuclear receptor-interacting protein 1 antibody|Receptor interacting protein 140 antibody|Receptor-interacting protein 140 antibody|RIP 140 antibody|RIP140 antibody

ID gène: 8204

UniProt: P48552

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway