Neuropilin 1 anticorps (AA 504-827)

N° du produit ABIN3043584

Détail du produit anti-Neuropilin 1 anticorps

Antigène: Neuropilin 1 (NRP1)

Épitope: AA 504-827

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neuropilin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Neuropilin-1(NRP1) detection. Tested with WB, IHC-P in Human,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Neuropilin-1(NRP1) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: neuropilin 1
Protein Name: Neuropilin-1

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Neuropilin 1 recombinant protein (Position: K504-T827). Human Neuropilin 1 shares 95% and 94% amino acid (aa) sequences identity with mouse and rat Neuropilin 1, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for Neuropilin 1 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-Neuropilin 1 (ABIN3043584)

Liu, Mei, Xu, Yu, Shi, Zhang, Wang, Zhang, Gao, Zhang, He: "Dual Receptor Recognizing Cell Penetrating Peptide for Selective Targeting, Efficient Intratumoral Diffusion and Synthesized Anti-Glioma Therapy." dans: Theranostics, Vol. 6, Issue 2, pp. 177-91, (2017) (PubMed).

Détails sur Neuropilin 1

Antigène: Neuropilin 1 (NRP1)

Autre désignation: NRP1 (NRP1 Produits)

Synonymes: anticorps NRP1, anticorps cd304, anticorps neuropilin, anticorps np-1, anticorps npn-1, anticorps nrp, anticorps nrp-1, anticorps vegf165r, anticorps BDCA4, anticorps CD304, anticorps NP1, anticorps NRP, anticorps VEGF165R, anticorps C530029I03, anticorps NP-1, anticorps NPN-1, anticorps Npn1, anticorps Nrp, anticorps neuropilin 1, anticorps neuropilin 1 L homeolog, anticorps NRP1, anticorps nrp1, anticorps Nrp1, anticorps nrp1.L

Sujet: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contain a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Synonyms: A5 protein antibody|BDCA4 antibody|BLOOD DENDRITIC CELL ANTIGEN 4 antibody|CD 304 antibody|CD304 antibody|DKFZp686A03134 antibody|DKFZp781F1414 antibody|Neuropilin-1 antibody|Neuropilin1 antibody|Neuropilin1 transmembrane receptor antibody|NP1 antibody|NPN1 antibody|NRP 1 antibody|NRP antibody|NRP1 antibody|NRP1_HUMAN antibody|Vascular endothelial cell growth factor 165 receptor antibody|VEGF165R antibody

ID gène: 8829

UniProt: O14786

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals