MBD2 anticorps (AA 159-411)

N° du produit ABIN3043613

Détail du produit anti-MBD2 anticorps

Antigène: MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

Épitope: AA 159-411

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBD2 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Methyl-CpG-binding domain protein 2(MBD2) detection. Tested with WB in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Methyl-CpG-binding domain protein 2(MBD2) detection. Tested with WB in Human.
Gene Name: methyl-CpG binding domain protein 2
Protein Name: Methyl-CpG-binding domain protein 2

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MBD2 recombinant protein (Position: W159-A411). Human MBD2 shares 98% amino acid (aa) sequence identity with mouse MBD2.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for MBD2 is approximately 0.2 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur MBD2

Antigène: MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

Autre désignation: MBD2 (MBD2 Produits)

Synonymes: anticorps MBD2, anticorps DMTase, anticorps NY-CO-41, anticorps MBD2a, anticorps wu:fa97f06, anticorps zgc:111862, anticorps methyl-CpG binding domain protein 2, anticorps methyl-CpG binding domain protein 2 S homeolog, anticorps MBD2, anticorps Mbd2, anticorps mbd2, anticorps mbd2.S

Sujet: Methyl-CpG-binding domain protein 2 is a protein that in humans is encoded by the MBD2 gene. It is mapped to 18q21.2. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG-binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.

Synonyms: DEMETHYLASE antibody|DKFZp586O0821 antibody|DMTase antibody|MBD 2 antibody|Mbd2 antibody|MBD2_HUMAN antibody|MBD2a antibody|Methyl CpG binding domain protein 2 antibody|Methyl CpG binding protein MBD2 antibody|Methyl-CpG-binding domain protein 2 antibody|Methyl-CpG-binding protein MBD2 antibody|NY CO 41 antibody

ID gène: 8932

Pathways: Chromatin Binding