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MBD2 anticorps (AA 159-411)

MBD2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3043613
  • Antigène Voir toutes MBD2 Anticorps
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Épitope
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 159-411
    Reactivité
    • 47
    • 23
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 44
    • 2
    • 1
    Lapin
    Clonalité
    • 44
    • 3
    Polyclonal
    Conjugué
    • 25
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MBD2 est non-conjugé
    Application
    • 40
    • 22
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Fonction
    Rabbit IgG polyclonal antibody for Methyl-CpG-binding domain protein 2(MBD2) detection. Tested with WB in Human.
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Methyl-CpG-binding domain protein 2(MBD2) detection. Tested with WB in Human.
    Gene Name: methyl-CpG binding domain protein 2
    Protein Name: Methyl-CpG-binding domain protein 2
    Purification
    Immunogen affinity purified.
    Immunogène
    E.coli-derived human MBD2 recombinant protein (Position: W159-A411). Human MBD2 shares 98% amino acid (aa) sequence identity with mouse MBD2.
    Isotype
    IgG
    Top Product
    Discover our top product MBD2 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for MBD2 is approximately 0.2 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Antigène
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Autre désignation
    MBD2 (MBD2 Produits)
    Synonymes
    anticorps MBD2, anticorps DMTase, anticorps NY-CO-41, anticorps MBD2a, anticorps wu:fa97f06, anticorps zgc:111862, anticorps methyl-CpG binding domain protein 2, anticorps methyl-CpG binding domain protein 2 S homeolog, anticorps MBD2, anticorps Mbd2, anticorps mbd2, anticorps mbd2.S
    Sujet
    Methyl-CpG-binding domain protein 2 is a protein that in humans is encoded by the MBD2 gene. It is mapped to 18q21.2. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG-binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.

    Synonyms: DEMETHYLASE antibody|DKFZp586O0821 antibody|DMTase antibody|MBD 2 antibody|Mbd2 antibody|MBD2_HUMAN antibody|MBD2a antibody|Methyl CpG binding domain protein 2 antibody|Methyl CpG binding protein MBD2 antibody|Methyl-CpG-binding domain protein 2 antibody|Methyl-CpG-binding protein MBD2 antibody|NY CO 41 antibody
    ID gène
    8932
    Pathways
    Chromatin Binding
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