Cytochrome C anticorps (C-Term)

N° du produit ABIN3043697

Détail du produit anti-Cytochrome C anticorps

Antigène: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Épitope: AA 91-105, C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cytochrome C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Fonction: Rabbit IgG polyclonal antibody for Cytochrome c(CYCS) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.

Séquence: ERADLIAYLK KATNE

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Cytochrome c(CYCS) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: cytochrome c, somatic
Protein Name: Cytochrome c

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Cytochrome C(91-105 aa ERADLIAYLKKATNE), identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-Cytochrome C (ABIN3043697)

Bai, Yang, Luo: "Effects of 5-hydroxy-4'-nitro-7-propionyloxy-genistein on inhibiting proliferation and invasion via activating reactive oxygen species in human ovarian cancer A2780/DDP cells." dans: Oncology letters, Vol. 15, Issue 4, pp. 5227-5235, (2018) (PubMed).

Jiao, Ma, Wang, Li, Shan, Sun, Chen: "Methacryloxylethyl Cetyl Ammonium Chloride Induces DNA Damage and Apoptosis in Human Dental Pulp Cells via Generation of Oxidative Stress." dans: International journal of biological sciences, Vol. 12, Issue 5, pp. 580-93, (2017) (PubMed).

Hu, Sun, Zhang, Zhang, Hu: "Catalpol inhibits apoptosis in hydrogen peroxide-induced cardiac myocytes through a mitochondrial-dependent caspase pathway." dans: Bioscience reports, Vol. 36, Issue 3, (2017) (PubMed).

Gan, Liu, Cao, Zhang, Sun: "FABP4 reversed the regulation of leptin on mitochondrial fatty acid oxidation in mice adipocytes." dans: Scientific reports, Vol. 5, pp. 13588, (2016) (PubMed).

Han, Liu, Li, Tian, Han, Wang, Fu, Guo, Zhu, Du, Tian: "HOXB1 Is a Tumor Suppressor Gene Regulated by miR-3175 in Glioma." dans: PLoS ONE, Vol. 10, Issue 11, pp. e0142387, (2016) (PubMed).

Jiao, Ma, Wang, Li, Shan, Liu, Liu, Song, Yu, Yu, Liu, Huang, Chen: "N-Acetyl Cysteine Depletes Reactive Oxygen Species and Prevents Dental Monomer-Induced Intrinsic Mitochondrial Apoptosis In Vitro in Human Dental Pulp Cells." dans: PLoS ONE, Vol. 11, Issue 1, pp. e0147858, (2016) (PubMed).

Ji, Geng, Zhou, Wei, Chen: "Chinese herbal medicine Yougui Pill reduces exogenous glucocorticoid-induced apoptosis in anterior pituitary cells." dans: Neural regeneration research, Vol. 11, Issue 12, pp. 1962-1968, (2016) (PubMed).

Xu, Liu, Zhang, Wang, Wang, Yang, Huo, Sun: "Apoptosis-related protein expression in rabbits with blast brain injury following early hyperbaric oxygen therapy." dans: Neural regeneration research, Vol. 7, Issue 17, pp. 1318-24, (2015) (PubMed).

Ding, Wang, Zhao, Sun, Zhai: "Protective Effects of Baicalin on A?????-Induced Learning and Memory Deficit, Oxidative Stress, and Apoptosis in Rat." dans: Cellular and molecular neurobiology, Vol. 35, Issue 5, pp. 623-32, (2015) (PubMed).

Li, Wang, Wang: "Radioprotective activity of neutral polysaccharides isolated from the fruiting bodies of Hohenbuehelia serotina." dans: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), Vol. 31, Issue 4, pp. 352-9, (2015) (PubMed).

Huang, Lin, Su, Ye: "Forsythiaside protects against hydrogen peroxide-induced oxidative stress and apoptosis in PC12 cell." dans: Neurochemical research, Vol. 40, Issue 1, pp. 27-35, (2015) (PubMed).

Zhang, Liu, Wang, Jin, Du, Peng, Xue: "Benzo(a)pyrene-7,8-diol-9,10-epoxide induced p53-independent necrosis via the mitochondria-associated pathway involving Bax and Bak activation." dans: Human & experimental toxicology, Vol. 34, Issue 2, pp. 179-90, (2015) (PubMed).

Jiang, Li, Zhou, Wang, Zhang, Wang: "Colistin-induced apoptosis in PC12 cells: involvement of the mitochondrial apoptotic and death receptor pathways." dans: International journal of molecular medicine, Vol. 33, Issue 5, pp. 1298-304, (2014) (PubMed).

Wei, Tian, Yan, Shao, Xie: "Protective effects of phillyrin on H2O 2-induced oxidative stress and apoptosis in PC12 cells." dans: Cellular and molecular neurobiology, Vol. 34, Issue 8, pp. 1165-73, (2014) (PubMed).

Ban, Fan, Huang, Li, Chen, Zhang, Xu: "Mono-(2-ethylhexyl) phthalate induces injury in human umbilical vein endothelial cells." dans: PLoS ONE, Vol. 9, Issue 5, pp. e97607, (2014) (PubMed).

Lin, Tongyi: "Role of Bax/Bcl-2 family members in green tea polyphenol induced necroptosis of p53-deficient Hep3B cells." dans: Tumour biology, Vol. 35, Issue 8, pp. 8065-75, (2014) (PubMed).

Mo, Chen, Huang, Zhang, Li, Zhou: "Neuroprotective effect of tea polyphenols on oxyhemoglobin induced subarachnoid hemorrhage in mice." dans: Oxidative medicine and cellular longevity, Vol. 2013, pp. 743938, (2014) (PubMed).

Song, Yue, Li, Li, Zhao, Zhang: "Study of the mechanism of sonodynamic therapy in a rat glioma model." dans: OncoTargets and therapy, Vol. 7, pp. 1801-10, (2014) (PubMed).

Li, Li, Huang, Kan, Wang, Wu, Yin, Yao: "Dexamethasone and A???-?? accelerate learning and memory impairments due to elevate amyloid precursor protein expression and neuronal apoptosis in 12-month male rats." dans: Behavioural brain research, Vol. 227, Issue 1, pp. 142-9, (2011) (PubMed).

Détails sur Cytochrome C

Antigène: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Autre désignation: CYCS (CYCS Produits)

Synonymes: anticorps CYC, anticorps HCS, anticorps THC4, anticorps cyct, anticorps cyc, anticorps hcs, anticorps CYCS, anticorps cytc, anticorps CYCSA, anticorps CG17903, anticorps Cyt C, anticorps Cyt c, anticorps Cyt-c2, anticorps CytC-2, anticorps Cytc, anticorps Cytc-p, anticorps DC4, anticorps DMc01, anticorps Dmel\\CG17903, anticorps cyt c, anticorps cyt c-p, anticorps cyt-c-p, anticorps cyt-c2, anticorps cyt.c, anticorps cytochrome c, anticorps dc4, anticorps pDMc01, anticorps wu:fk52b01, anticorps zgc:86706, anticorps ENSMUSG00000058927, anticorps cytochrome c, somatic, anticorps cytochrome c, somatic S homeolog, anticorps Cytochrome c proximal, anticorps cytochrome c, somatic b, anticorps cytochrome c, somatic pseudogene, anticorps cytochrome c-like, anticorps cytochrome c, anticorps CYCS, anticorps cycs.S, anticorps cycs, anticorps Cycs, anticorps Cyt-c-p, anticorps cycsb, anticorps Gm10053, anticorps LOC100724240, anticorps CYC, anticorps LOC100847700, anticorps LOC101107954, anticorps LOC106829744, anticorps LOC106992390, anticorps LOC102085712

Sujet: Cytochrome C is located in the mitochondria of all aerobic cells and is involved in the electron transport system. Human cytochrome c has 104 amino acid residues and a molecular weight of 11,458 and is mapped to 7p15.2. Cytochrome c released from mitochondria has been proposed to be an essential component of an apoptotic pathway responsive to DNA damage and other forms of cell stress. And it has a role in different apoptotic signaling cascades.

Synonyms: CYC antibody|CYC_HUMAN antibody|CYCS antibody|Cytochrome c antibody|Cytochrome c somatic antibody|HCS antibody|THC4 antibody

UniProt: P99999

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity