ALOX15 anticorps (AA 2-337)

N° du produit ABIN3043726

Détail du produit anti-ALOX15 anticorps

Antigène: ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

Épitope: AA 2-337

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALOX15 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Arachidonate 15-lipoxygenase(ALOX15) detection. Tested with WB, IHC-P in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Arachidonate 15-lipoxygenase(ALOX15) detection. Tested with WB, IHC-P in Human.
Gene Name: arachidonate 15-lipoxygenase
Protein Name: Arachidonate 15-lipoxygenase

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ALOX15 recombinant protein (Position: G2-P337). Human ALOX15 shares 72% and 73% amino acid (aa) sequences identity with mouse and rat ALOX15, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for ALOX15 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur ALOX15

Antigène: ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

Autre désignation: ALOX15 (ALOX15 Produits)

Synonymes: anticorps 15-LOX-1, anticorps 15LOX-1, anticorps ALOX15, anticorps 12-LO, anticorps Alox12l, anticorps L-12LO, anticorps 12-LOX, anticorps Alox12, anticorps ALOX12, anticorps 15-LOX, anticorps Alox12e, anticorps arachidonate 15-lipoxygenase, anticorps Arachidonate 15-lipoxygenase, anticorps ALOX15, anticorps Alox15, anticorps Nmul_A0532, anticorps Sden_1680, anticorps Swoo_2919, anticorps PCC8801_3106, anticorps Cyan8802_3014, anticorps Nwat_1315

Sujet: Arachidonate 15-lipoxygenase, also known as 15 LOX or LOG15, is an enzyme that in humans is encoded by the ALOX15 gene. This gene is mapped to 17p13.2. It is found that ALOX15 is a mutator gene. ALOX15 gene product is implicated in antiinflammation, membrane remodeling, and cancer development/metastasis. Loss of the TP53 gene, or gain-of-function activities resulting from the expression of its mutant forms regulates ALOX15 promoter activity in human and in mouse, albeit in directionally opposite manners.

Synonyms: 15 lipoxygenase 1 antibody|15 LIPOXYGENASE RETICULOCYTE ARACHIDONATE antibody|15 LOX antibody|15 LOX 1 antibody|15-LOX antibody|15LOX 1 antibody|ALOX15 antibody|Arachidonate 15 lipoxygenase antibody|Arachidonate 15-lipoxygenase antibody|Arachidonate omega 6 lipoxygenase antibody|Arachidonate omega-6 lipoxygenase antibody|LOG15 antibody|LOX15_HUMAN antibody

ID gène: 246

UniProt: P16050

Pathways: Regulation of Actin Filament Polymerization