Nerve Growth Factor anticorps (N-Term)

N° du produit ABIN3043754

Détail du produit anti-Nerve Growth Factor anticorps

Antigène: Nerve Growth Factor (NGF)

Épitope: AA 162-173, N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nerve Growth Factor est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Beta-nerve growth factor(NGF) detection. Tested with WB in Human,Mouse,Rat.

Séquence: EVNINNSVFK QY

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Beta-nerve growth factor(NGF) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: nerve growth factor(beta polypeptide)
Protein Name: Beta-nerve growth factor(Beta-NGF)

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human NGF(162-173aa EVNINNSVFKQY), identical to the related rat sequence, and different from the related mouse sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-Nerve Growth Factor (ABIN3043754)

Fan, Xiong, Fu, Xu, Wang, Chen, Xia, Peng, Ye, Wang, Zhang, Ye et al.: "Polyaniline promotes peripheral nerve regeneration by enhancement of the brain‑derived neurotrophic factor and ciliary neurotrophic factor expression and activation of the ERK1/2/MAPK signaling ..." dans: Molecular medicine reports, Vol. 16, Issue 5, pp. 7534-7540, (2018) (PubMed).

Luo, Liu, Chen, Wang, Zeng, Chen, Cheng et al.: "Nerve growth factor and inducible nitric oxide synthase expression in the mesencephalon and diencephalon, as well as visual- and auditory-related nervous tissues, in a macaque model of type 2 ..." dans: Neural regeneration research, Vol. 7, Issue 4, pp. 302-7, (2015) (PubMed).

Zhao, Chen, Shen, Zhao, Wang, Shi, Wang, Cui, Yan, Xue: "Transplantation of human umbilical cord blood mesenchymal stem cells to treat a rat model of traumatic brain injury." dans: Neural regeneration research, Vol. 7, Issue 10, pp. 741-8, (2015) (PubMed).

Lu, Liu, Zhu, Xu: "Expression of nerve growth factor and hypoxia inducible factor-1? and its correlation with angiogenesis in non-small cell lung cancer." dans: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 3, pp. 359-62, (2014) (PubMed).

Li, Ma, Yi, Wang, Li, Liu, Sun, Chen, Yu, Li, Chen, Zhou: "The interactions between nerve growth factor and gonadotrophins in bovine oviduct." dans: Animal reproduction science, Vol. 149, Issue 3-4, pp. 117-23, (2014) (PubMed).

Huang, Zhang, Xu, Li, Zhao: "Expression of nerve growth factor in the prostate of male rats in response to chronic stress and sympathetic denervation." dans: Experimental and therapeutic medicine, Vol. 8, Issue 4, pp. 1237-1240, (2014) (PubMed).

Zhao, Ding, Guo, Chen: "Intrathecal lidocaine neurotoxicity: combination with bupivacaine and ropivacaine and effect of nerve growth factor." dans: Life sciences, Vol. 112, Issue 1-2, pp. 10-21, (2014) (PubMed).

Li, Shu, Tang, Deng, Fu, Lv: "?-Nerve growth factor attenuates hepatocyte injury induced by D-galactosamine in vitro via TrkA NGFR." dans: Molecular medicine reports, Vol. 8, Issue 3, pp. 813-7, (2013) (PubMed).

Pu, Shi, Wang, Wang, Guo, Liu, Sun, Gao, Zhou: "Effects of minocycline on the expression of NGF and HSP70 and its neuroprotection role following intracerebral hemorrhage in rats." dans: Journal of biomedical research, Vol. 25, Issue 4, pp. 292-8, (2013) (PubMed).

Sun, Guo, Zheng, Zhang, Li, Liu, Yin, Yang, Shu: "Increased expression of TRPV1 in the cortex and hippocampus from patients with mesial temporal lobe epilepsy." dans: Journal of molecular neuroscience : MN, Vol. 49, Issue 1, pp. 182-93, (2012) (PubMed).

Orita, Koshi, Mitsuka, Miyagi, Inoue, Arai, Ishikawa, Hanaoka, Yamashita, Yamashita, Eguchi, Toyone, Takahashi, Ohtori: "Associations between proinflammatory cytokines in the synovial fluid and radiographic grading and pain-related scores in 47 consecutive patients with osteoarthritis of the knee." dans: BMC musculoskeletal disorders, Vol. 12, pp. 144, (2012) (PubMed).

Wang, Zhao, Fan, Gong, Li, Qi, Liu: "Research on the mechanism of Zuogui Pill and Yougui Pill in promoting axonal regeneration in model rats of autoimmune encephalomyelitis." dans: Chinese journal of integrative medicine, Vol. 16, Issue 2, pp. 167-72, (2010) (PubMed).

Détails sur Nerve Growth Factor

Antigène: Nerve Growth Factor (NGF)

Autre désignation: NGF (NGF Produits)

Synonymes: anticorps Beta-NGF, anticorps HSAN5, anticorps NGFB, anticorps Ngfb, anticorps ngfb, anticorps ns:zft386, anticorps xx:zft386, anticorps zgc:109730, anticorps beta-NGF, anticorps hsan5, anticorps beta-ngf, anticorps NGF, anticorps ngf, anticorps nerve growth factor, anticorps nerve growth factor b (beta polypeptide), anticorps nerve growth factor S homeolog, anticorps NGF, anticorps Ngf, anticorps ngfb, anticorps ngf, anticorps ngf.S

Sujet: Nerve growth factor is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. The nucleotide sequence of human and mouse beta-NGF are very similar. The beta-subunits of nerve growth factor(NGFB) have been assigned to mouse chromosome 3 and human chromosome 1p22. The human gene for the beta subunit of nerve growth factor is located on the proximal short arm of chromosome 1. A mutation in the nerve growth factor beta gene(NGFB) causes loss of pain perception.

Synonyms: Beta nerve growth factor antibody|Beta nerve growth factor precursor antibody|Beta NGF antibody|Beta-nerve growth factor antibody|Beta-NGF antibody|HSAN5 antibody|MGC161426 antibody|MGC161428 antibody|Nerve growth factor beta antibody|Nerve growth factor beta polypeptide antibody|Nerve growth factor beta subunit antibody|NGF antibody|NGF B antibody|NGF_HUMAN antibody|NGFB antibody|NID67 antibody

UniProt: P01138

Pathways: Regulation of Cell Size