Glutamate Receptor 1 anticorps (AA 19-360)

N° du produit ABIN3043837

Détail du produit anti-Glutamate Receptor 1 anticorps

Antigène: Glutamate Receptor 1 (GLUR1)

Épitope: AA 19-360

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutamate Receptor 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Glutamate receptor 1(GRIA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Glutamate receptor 1(GRIA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: glutamate receptor, ionotropic, AMPA 1
Protein Name: Glutamate receptor 1

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GRIA1 recombinant protein (Position: A19-R360). Human GRIA1 shares 98% amino acid (aa) sequence identity with both mouse and rat GRIA1.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for GRIA1 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-Glutamate Receptor 1 (ABIN3043837)

Liu, Mei, Li, Roboti, Pang, Ying, Gao, Lowe, Bao: "Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 2, pp. 346-351, (2018) (PubMed).

Détails sur Glutamate Receptor 1

Antigène: Glutamate Receptor 1 (GLUR1)

Autre désignation: GRIA1 (GLUR1 Produits)

Synonymes: anticorps GLUH1, anticorps GLUR1, anticorps GLURA, anticorps GluA1, anticorps HBGR1, anticorps gluR-A, anticorps 2900051M01Rik, anticorps Glr-1, anticorps Glr1, anticorps GluR-A, anticorps GluRA, anticorps Glur-1, anticorps Glur1, anticorps HIPA1, anticorps gluR-K1, anticorps GRIA1, anticorps glur1, anticorps Gria1, anticorps glur1b, anticorps gria1.2, anticorps sb:eu293, anticorps ZfGluR1a, anticorps glur1a, anticorps gria1.1, anticorps zfGRIA1[a], anticorps glutamate ionotropic receptor AMPA type subunit 1, anticorps glutamate receptor, ionotropic, AMPA1 (alpha 1), anticorps glutamate receptor, ionotropic, AMPA 1, anticorps glutamate receptor, ionotropic, AMPA 1 L homeolog, anticorps GluR1 protein, anticorps Glutamate receptor 1, anticorps glutamate receptor, ionotropic, AMPA 1b, anticorps glutamate receptor, ionotropic, AMPA 1a, anticorps GRIA1, anticorps Gria1, anticorps gria1, anticorps gria1.L, anticorps glur1, anticorps glr-1, anticorps gria1b, anticorps gria1a

Sujet: GLUR1, Glutamate receptor 1, is a protein that in humans is encoded by the GLUR1 gene. GLUR1 mRNA is widely expressed in human brain. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Each of the members (GRIA1-4) include flip and flop isoforms generated by alternative RNA splicing. The receptor subunits encoded by each isoform vary in their signal transduction properties. The isoform presented here is the flop isoform. In situ hybridization experiments showed that human GRIA1 mRNA is present in granule and pyramidal cells in the hippocampal formation.

Synonyms: GLUR 1 antibody|GLUR A antibody|AMPA 1 antibody|AMPA selective glutamate receptor 1 antibody|AMPA-selective glutamate receptor 1 antibody|GluA1 antibody|GLUH 1 antibody|GLUH1 antibody|GluR K1 antibody|GluR-1 antibody|GluR-A antibody|GluR-K1 antibody|GLUR1 antibody|GLURA antibody|GluRK1 antibody|Glutamate receptor 1 antibody|Glutamate receptor ionotropic AMPA 1 antibody|Glutamate receptor ionotropic antibody|Glutamate receptor, ionotropic, AMPA 1 antibody|Gria 1 antibody|Gria1 antibody|GRIA1_HUMAN antibody|HBGR1 antibody|MGC133252 antibody|OTTHUMP00000160643 antibody|OTTHUMP00000165781 antibody|OTTHUMP00000224241 antibody|OTTHUMP00000224242 antibody|OTTHUMP00000224243 antibody

ID gène: 2890

UniProt: P42261

Pathways: Signalisation PI3K-Akt