SIRT2 anticorps (Middle Region)

N° du produit ABIN3043924

Détail du produit anti-SIRT2 anticorps

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Épitope: AA 165-187, Middle Region

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for NAD-dependent protein deacetylase sirtuin-2(SIRT2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: YTQNIDTLER IAGLEQEDLV EAH

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for NAD-dependent protein deacetylase sirtuin-2(SIRT2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: sirtuin 2
Protein Name: NAD-dependent protein deacetylase sirtuin-2

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human SIRT2(165-187aa YTQNIDTLERIAGLEQEDLVEAH), different from the related mouse and rat sequences by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for SIRT2 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur SIRT2

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Autre désignation: SIRT2 (SIRT2 Produits)

Synonymes: anticorps CG5085, anticorps D.mel2, anticorps Dmel\\CG5085, anticorps SIRT2, anticorps dSIRT2, anticorps sir2, anticorps Sirt2, anticorps BmSirt2, anticorps AtSRT2, anticorps SIRTUIN 2, anticorps T2K12.8, anticorps sirtuin 2, anticorps SIR2, anticorps SIR2L, anticorps SIR2L2, anticorps 5730427M03Rik, anticorps Sir2l, anticorps wu:fb57d05, anticorps zgc:55966, anticorps zgc:77003, anticorps Sirtuin 2, anticorps sirtuin 2, anticorps sirtuin 2 S homeolog, anticorps NAD-dependent deacetylase sirtuin 2 homolog, anticorps sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae), anticorps Sirt2, anticorps SIRT2, anticorps sirt2.S, anticorps SRT2, anticorps sirt2

Sujet: SIRT2 is a predominantly cytoplasmic protein that colocalizes with microtubules. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. SIRT2 is mapped to 19q13.2. It is able to cause radioactivity to be transferred from (32P) NAD to bovine serum albumin (BSA). According to researches, SIRT2 can act as a bona fide tubulin deacetylase. SIRT2 was found to deacetylate lys40 of alpha-tubulin both in vitro and in vivo. SIRT2 is also a regulator of mitotic progression that acts downstream from CDC14B in a pathway regulating mitotic exit or subsequent cytokinesis. What's more, SIRT2 is an important regulator of programmed necrosis.

Synonyms: FLJ35621 antibody|FLJ37491 antibody|NAD dependent deacetylase sirtuin 2 antibody|NAD-dependent deacetylase sirtuin-2 antibody|NAD-dependent protein deacetylase sirtuin-2 antibody|Regulatory protein SIR2 homolog 2 antibody|Silencing information regulator 2 like antibody|Silent information regulator 2 antibody|Silent mating type information regulation 2 antibody|Silent mating type information regulation 2 homolog antibody|SIR 2 antibody|SIR2 antibody|SIR2 like antibody|SIR2 like protein 2 antibody|Sir2 related protein type 2 antibody|SIR2, S. cerevisiae, homolog-loke 2 antibody|SIR2-like protein 2 antibody|SIR2L antibody|SIR2L2 antibody|SIRT 2 antibody|SIRT2 antibody|SIRT2_HUMAN antibody|Sirtuin (silent mating type information regulation 2 homolog) 2 (S.cerevisiae) antibody|Sirtuin 2 antibody|Sirtuin type 2 antibody|Sirtuin2 antibody

ID gène: 22933