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WASP anticorps (C-Term)

WAS Reactivité: Humain, Souris, Rat WB, IHC (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3043961
  • Antigène Voir toutes WASP (WAS) Anticorps
    WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
    Épitope
    • 15
    • 14
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 129-156, C-Term
    Reactivité
    • 88
    • 55
    • 18
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 84
    • 4
    • 1
    Lapin
    Clonalité
    • 85
    • 4
    Polyclonal
    Conjugué
    • 35
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp WASP est non-conjugé
    Application
    • 63
    • 39
    • 27
    • 16
    • 13
    • 13
    • 8
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Fonction
    Rabbit IgG polyclonal antibody for Wiskott-Aldrich syndrome protein(WAS) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
    Séquence
    ADEDEAQAFR ALVQEKIQKR NQRQSGDR
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Wiskott-Aldrich syndrome protein(WAS) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
    Gene Name: Wiskott-Aldrich syndrome
    Protein Name: Wiskott-Aldrich syndrome protein
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence at the C-terminus of human WASP (129-156aa ADEDEAQAFRALVQEKIQKRNQRQSGDR), different from the related mouse sequence by two amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product WAS Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for WASP is approximately 0.1 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Antigène
    WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
    Autre désignation
    WAS (WAS Produits)
    Synonymes
    anticorps IMD2, anticorps SCNX, anticorps THC, anticorps THC1, anticorps WASP, anticorps U42471, anticorps WASp, anticorps Wasp, anticorps imd2, anticorps thc, anticorps thc1, anticorps was, anticorps wasp, anticorps wu:fk81c08, anticorps zgc:64164, anticorps Wiskott-Aldrich syndrome, anticorps neural Wiskott-Aldrich syndrome protein, anticorps wiskott-aldrich syndrome protein, anticorps Wiskott-Aldrich syndrome L homeolog, anticorps Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b, anticorps WAS, anticorps LOC5578888, anticorps CpipJ_CPIJ006699, anticorps Was, anticorps was.L, anticorps wasb
    Sujet
    The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.

    Synonyms: Eczema thrombocytopenia antibody|IMD2 antibody|SCNX antibody|THC antibody|THC1 antibody| Thrombocytopenia 1 (X linked) antibody|U42471 antibody|Was antibody|WAS protein antibody| WASp antibody|WASP_HUMAN antibody|Wiskott Aldrich syndrome (eczema thrombocytopenia) antibody|Wiskott Aldrich syndrome (eczema thrombocytopenia) protein antibody|Wiskott Aldrich syndrome antibody|Wiskott Aldrich syndrome protein antibody|Wiskott-Aldrich syndrome protein antibody
    ID gène
    7454
    UniProt
    P42768
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