EGR1 anticorps (N-Term)

N° du produit ABIN3043997

Détail du produit anti-EGR1 anticorps

Antigène: EGR1 (Early Growth Response 1 (EGR1))

Épitope: AA 23-43, N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EGR1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Fonction: Rabbit IgG polyclonal antibody for Early growth response protein 1(EGR1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.

Séquence: FPHSPTMDNY PKLEEMMLLS N

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Early growth response protein 1(EGR1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: early growth response 1
Protein Name: Early growth response protein 1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Egr1(23-43aa FPHSPTMDNYPKLEEMMLLSN), identical to the related rat and mouse sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Références pour anticorps anti-EGR1 (ABIN3043997)

Lin, Fang, Cai, Huang, Zhang, Lu, Zhang, Wei: "ERK/Egr-1 signaling pathway is involved in CysLT2 receptor-mediated IL-8 production in HEK293 cells." dans: European journal of cell biology, Vol. 93, Issue 7, pp. 278-88, (2014) (PubMed).

Détails sur EGR1

Antigène: EGR1 (Early Growth Response 1 (EGR1))

Autre désignation: EGR1 (EGR1 Produits)

Synonymes: anticorps AT225, anticorps G0S30, anticorps KROX-24, anticorps NGFI-A, anticorps TIS8, anticorps ZIF-268, anticorps ZNF225, anticorps A530045N19Rik, anticorps ETR103, anticorps Egr-1, anticorps Krox-1, anticorps Krox-24, anticorps Krox24, anticorps NGF1-A, anticorps NGFIA, anticorps Zenk, anticorps Zfp-6, anticorps Zif268, anticorps egr, anticorps Ngf1, anticorps Ngfi, anticorps zif-268, anticorps EGR1, anticorps EGR-1-A, anticorps Xegr-1, anticorps at225, anticorps egr-1, anticorps egr1, anticorps g0s30, anticorps krox-24, anticorps ngfi-a, anticorps tis8, anticorps znf225, anticorps krox24, anticorps wu:fj64b05, anticorps wu:fq25f01, anticorps EGR-1, anticorps zenk, anticorps EGR-1-B, anticorps egr1-a, anticorps egr1-b, anticorps early growth response 1, anticorps early growth response protein 1 (egr-1), anticorps early growth response 1 L homeolog, anticorps early growth response 1 S homeolog, anticorps EGR1, anticorps CNK00890, anticorps Egr1, anticorps egr1.L, anticorps egr1, anticorps egr1.S

Sujet: Earlu growth response protein 1, also known as ZIF268 or NGFIA, is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. This gene is mapped to 5q31.2. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. It has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity.

Synonyms: AT 225 antibody|AT225 antibody|Early growth response 1 antibody|Early growth response protein 1 antibody|EGR 1 antibody|EGR-1 antibody|EGR1 antibody|EGR1_HUMAN antibody|G0S 30 antibody|G0S30 antibody|KROX 24 antibody|Krox 24 protein antibody|KROX24 antibody|Nerve growth factor induced protein A antibody|Nerve growth factor-induced clone A antibody|Nerve growth factor-induced protein A antibody|NGFI A antibody|NGFI-A antibody|NGFIA antibody|TIS 8 antibody|TIS8 antibody|Transcription factor ETR 103 antibody|Transcription factor ETR103 antibody|Transcription factor Zif 268 antibody|Transcription factor Zif268 antibody|Zfp 6 antibody|ZIF 268 antibody|ZIF268 antibody|Zinc finger protein 225 antibody|Zinc finger protein Krox-24 antibody|ZNF 225 antibody|ZNF225 antibody

UniProt: P18146

Pathways: Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity