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POR anticorps (C-Term)

POR Reactivité: Humain, Rat WB, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3044023
  • Antigène Voir toutes POR Anticorps
    POR (P450 (Cytochrome) Oxidoreductase (POR))
    Épitope
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 659-677, C-Term
    Reactivité
    • 48
    • 33
    • 29
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat
    Hôte
    • 46
    • 6
    • 2
    • 1
    Lapin
    Clonalité
    • 43
    • 12
    Polyclonal
    Conjugué
    • 33
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Cet anticorp POR est non-conjugé
    Application
    • 36
    • 19
    • 11
    • 10
    • 9
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Fonction
    Rabbit IgG polyclonal antibody for NADPH--cytochrome P450 reductase(POR) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    Séquence
    DYIKKLMTKG RYSLDVWS
    Réactivité croisée (Details)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Attributs du produit
    Rabbit IgG polyclonal antibody for NADPH--cytochrome P450 reductase(POR) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    Gene Name: P450(cytochrome) oxidoreductase
    Protein Name: NADPH--cytochrome P450 reductase
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence at the C-terminus of human POR (659-677aa DYIKKLMTKGRYSLDVWS), different from the related rat and mouse sequences by one amino acid.
    Isotype
    IgG
    Top Product
    Discover our top product POR Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Thimerosal (Merthiolate), Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Date de péremption
    12 months
  • Antigène
    POR (P450 (Cytochrome) Oxidoreductase (POR))
    Autre désignation
    POR (POR Produits)
    Synonymes
    anticorps CPR, anticorps CYPOR, anticorps P450R, anticorps POR, anticorps CCR, anticorps CG11567, anticorps DMR, anticorps DmCPR, anticorps Dmel\\CG11567, anticorps NCPR, anticorps P450, anticorps cpr, anticorps zgc:110032, anticorps npr, anticorps xpor, anticorps 4933424M13Rik, anticorps PORCINO, anticorps T5J17.90, anticorps T5J17_90, anticorps TFC C, anticorps TUBULIN-FOLDING COFACTOR C, anticorps cytochrome p450 oxidoreductase, anticorps P450 (cytochrome) oxidoreductase, anticorps ADP-ribosylation factor interacting protein 2, anticorps Cytochrome P450 reductase, anticorps P450 (cytochrome) oxidoreductase a, anticorps P450 (cytochrome) oxidoreductase L homeolog, anticorps NADPH--cytochrome P450 reductase, anticorps C-CAP/cofactor C-like domain-containing protein, anticorps POR, anticorps Arfip2, anticorps Por, anticorps Cpr, anticorps pora, anticorps por.L, anticorps LOC100406157, anticorps por, anticorps LOC100619047
    Sujet
    POR is a membrane-boundenzyme required for electron transfer from NADPH to cytochrome P450 in the endoplasmic reticulum of theeukaryotic cell. The gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

    Synonyms: CPR antibody|CYPOR antibody|DKFZp686G04235 antibody|FLJ26468 antibody|NADPH Cytochrome P450 Reductase antibody|NADPH dependent cytochrome P450 reductase antibody|NADPH--cytochrome P450 reductase antibody|NCPR_HUMAN antibody|P450(cytochrome) oxidoreductase antibody|P450 Cytochrome Oxidoreductase antibody|P450R antibody|POR antibody
    UniProt
    P16435
    Pathways
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome
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