HSPB2 anticorps (Middle Region)

N° du produit ABIN3044185

Détail du produit anti-HSPB2 anticorps

Antigène: HSPB2 (Heat Shock 27kDa Protein 2 (HSPB2))

Épitope: AA 102-118, Middle Region

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSPB2 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Fonction: Rabbit IgG polyclonal antibody for Heat shock protein beta-2(HSPB2) detection. Tested with WB, IHC-F, ICC in Human,Mouse,Rat.

Séquence: RHPQRLDRHG FVSREFC

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Heat shock protein beta-2(HSPB2) detection. Tested with WB, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: heat shock 27 kDa protein 2(HspB2)
Protein Name: Heat shock protein beta-2(HspB2)

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human HSPB2(102-118aa RHPQRLDRHGFVSREFC), identical to the related rat and mouse sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(F) and ICC.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur HSPB2

Antigène: HSPB2 (Heat Shock 27kDa Protein 2 (HSPB2))

Autre désignation: HSPB2 (HSPB2 Produits)

Synonymes: anticorps zgc:112532, anticorps HSP27, anticorps Hs.78846, anticorps LOH11CR1K, anticorps MKBP, anticorps 27kDa, anticorps 2810021G24Rik, anticorps heat shock protein family B (small) member 2, anticorps heat shock protein, alpha-crystallin-related, b2, anticorps heat shock protein 2, anticorps HSPB2, anticorps hspb2, anticorps Hspb2

Sujet: Alpha-B-crystallin is a member of the alpha-crystallin/small heat-shock protein(HSP) family and under various neuropathologic conditions accumulates in reactive astrocytes and degenerating neurons. In the 5-prime flanking region of the CRYAB gene on 11q22-q23, where a constitutive DNaseI hypersensitive site is located, Iwaki et al.(1997) identified a gene transcribed in the opposite direction. Analysis of its mRNA structure by RT-PCR and 5-prime/3-prime RACE revealed that this gene is composed of 2 exons and encodes a new member of the alpha-crystallin/hsp family. They termed the gene HSPB2. Iwaki et al.(1997) also determined the complete genomic structure of the rat homolog of HSPB2. Southern blot analysis demonstrated that HSPB2is expressed preferentially in skeletal muscle and heart but not in the lens, while the neighboring CRYAB gene is highly expressed in all 3 tissues. The 2 related genes are arranged in a head-to-head manner with an intergenic sequence of less than 1 kb, raising a possibility of shared regulatory elements for their expression.

Synonyms: DMPK-binding protein antibody|Heat shock 27kD protein 2 antibody|Heat shock 27 kDa protein 2 antibody|Heat shock protein beta-2 antibody|Heat-shock protein beta-2 antibody|Hs.78846 antibody|HSP27 antibody|HspB2 antibody|HSPB2_HUMAN antibody|LOH11CR1K antibody|MGC133245 antibody|MKBP antibody

UniProt: Q16082