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HSPB2 anticorps (Middle Region)

HSPB2 Reactivité: Humain, Rat WB, ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3044185
  • Antigène Voir toutes HSPB2 Anticorps
    HSPB2 (Heat Shock 27kDa Protein 2 (HSPB2))
    Épitope
    • 15
    • 12
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 102-118, Middle Region
    Reactivité
    • 39
    • 27
    • 26
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Humain, Rat
    Hôte
    • 54
    • 2
    Lapin
    Clonalité
    • 54
    • 2
    Polyclonal
    Conjugué
    • 25
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HSPB2 est non-conjugé
    Application
    • 43
    • 15
    • 15
    • 14
    • 13
    • 13
    • 13
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Fonction
    Rabbit IgG polyclonal antibody for Heat shock protein beta-2(HSPB2) detection. Tested with WB, IHC-F, ICC in Human,Mouse,Rat.
    Séquence
    RHPQRLDRHG FVSREFC
    Réactivité croisée (Details)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Heat shock protein beta-2(HSPB2) detection. Tested with WB, IHC-F, ICC in Human,Mouse,Rat.
    Gene Name: heat shock 27 kDa protein 2(HspB2)
    Protein Name: Heat shock protein beta-2(HspB2)
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence in the middle region of human HSPB2(102-118aa RHPQRLDRHGFVSREFC), identical to the related rat and mouse sequences.
    Isotype
    IgG
    Top Product
    Discover our top product HSPB2 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(F) and ICC.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Thimerosal (Merthiolate), Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Date de péremption
    12 months
  • Antigène
    HSPB2 (Heat Shock 27kDa Protein 2 (HSPB2))
    Autre désignation
    HSPB2 (HSPB2 Produits)
    Synonymes
    anticorps zgc:112532, anticorps HSP27, anticorps Hs.78846, anticorps LOH11CR1K, anticorps MKBP, anticorps 27kDa, anticorps 2810021G24Rik, anticorps heat shock protein family B (small) member 2, anticorps heat shock protein, alpha-crystallin-related, b2, anticorps heat shock protein 2, anticorps HSPB2, anticorps hspb2, anticorps Hspb2
    Sujet
    Alpha-B-crystallin is a member of the alpha-crystallin/small heat-shock protein(HSP) family and under various neuropathologic conditions accumulates in reactive astrocytes and degenerating neurons. In the 5-prime flanking region of the CRYAB gene on 11q22-q23, where a constitutive DNaseI hypersensitive site is located, Iwaki et al.(1997) identified a gene transcribed in the opposite direction. Analysis of its mRNA structure by RT-PCR and 5-prime/3-prime RACE revealed that this gene is composed of 2 exons and encodes a new member of the alpha-crystallin/hsp family. They termed the gene HSPB2. Iwaki et al.(1997) also determined the complete genomic structure of the rat homolog of HSPB2. Southern blot analysis demonstrated that HSPB2is expressed preferentially in skeletal muscle and heart but not in the lens, while the neighboring CRYAB gene is highly expressed in all 3 tissues. The 2 related genes are arranged in a head-to-head manner with an intergenic sequence of less than 1 kb, raising a possibility of shared regulatory elements for their expression.

    Synonyms: DMPK-binding protein antibody|Heat shock 27kD protein 2 antibody|Heat shock 27 kDa protein 2 antibody|Heat shock protein beta-2 antibody|Heat-shock protein beta-2 antibody|Hs.78846 antibody|HSP27 antibody|HspB2 antibody|HSPB2_HUMAN antibody|LOH11CR1K antibody|MGC133245 antibody|MKBP antibody
    UniProt
    Q16082
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