PMVK anticorps (Middle Region)

N° du produit ABIN3044328

Détail du produit anti-PMVK anticorps

Antigène: PMVK (Phosphomevalonate Kinase (PMVK))

Épitope: AA 135-151, Middle Region

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PMVK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Phosphomevalonate kinase(PMVK) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: EQSRQQRGWV FTPGVDD

Réactivité croisée (Details): Predicted Cross Reactivity: human, mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Phosphomevalonate kinase(PMVK) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: phosphomevalonate kinase
Protein Name: Phosphomevalonate kinase(PMKase/hPMK)

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human PMVK(135-151aa EQSRQQRGWVFTPGVDD), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur PMVK

Antigène: PMVK (Phosphomevalonate Kinase (PMVK))

Autre désignation: PMVK (PMVK Produits)

Synonymes: anticorps MPK_Bm, anticorps F5M6.9, anticorps F5M6_9, anticorps zgc:162701, anticorps HUMPMKI, anticorps PMK, anticorps PMKA, anticorps PMKASE, anticorps 1110011E12Rik, anticorps 2900002L22Rik, anticorps AV001327, anticorps phosphomevalonate kinase, anticorps GHMP kinase family protein, anticorps PMVK, anticorps Mpk, anticorps AT1G31910, anticorps CpipJ_CPIJ015413, anticorps Bm1_05275, anticorps pmvk, anticorps LOAG_11811, anticorps Tsp_06629, anticorps LOC100282968, anticorps Pmvk

Sujet: PMVK(phosphomevalonate kinase) is a cytosolic enzyme that catalyzes the conversion of mevalonate-5-phosphate to mevalonate-5-diphosphate. It is mapped to chromosome 1p13-1q22-23 and spans more than 8.4 kb in the human genome. PMVK is a peroxisomal protein which requires the C-terminal peroxisomal targeting signal, Ser-Arg-Leu, for localization to the organelle. It was expressed highly in heart, liver, skeletal muscle, kidney and pancreas and slightly lower in brain, placenta, and lung. And PMKase gene expression is subject to regulation by sterol at the level of transcription. It is a single copy gene covering less than 15 kb in the human genome. The human PMKase amino acid sequence contains a consensus peroxisomal targeting sequence(PTS-1), Ser-Arg-Leu, at the C terminus of the protein.

Synonyms: hPMK antibody|HUMPMKI antibody|OTTHUMP00000035546 antibody|Phosphomevalonate kinase antibody|PMK antibody|PMK PEN antibody|PMKA antibody|PMKase antibody|PMKI antibody|PMKPEN antibody|PMVK antibody|PMVK_HUMAN antibody

UniProt: Q15126