Pleiotrophin anticorps (C-Term)

N° du produit ABIN3044398

Détail du produit anti-Pleiotrophin anticorps

Antigène: Pleiotrophin (PTN)

Épitope: AA 150-168, C-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Pleiotrophin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Pleiotrophin(PTN) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: QAESKKKKKE GKKQEKMLD

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Pleiotrophin(PTN) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: pleiotrophin
Protein Name: Pleiotrophin(PTN)

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Pleiotrophin(150-168aa QAESKKKKKEGKKQEKMLD), identical to the related rat and mouse sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Références pour anticorps anti-Pleiotrophin (ABIN3044398)

Zhang, Liu, Liu, Zhou, Song, Cao, An: "miR-182 aids in receptive endometrium development in dairy goats by down-regulating PTN expression." dans: PLoS ONE, Vol. 12, Issue 7, pp. e0179783, (2017) (PubMed).

Détails sur Pleiotrophin

Antigène: Pleiotrophin (PTN)

Autre désignation: PTN (PTN Produits)

Synonymes: anticorps zHBNF, anticorps zgc:111787, anticorps harp, anticorps hbnf, anticorps X-PTF, anticorps hbgf8, anticorps negf1, anticorps ptn, anticorps PTN, anticorps HARP, anticorps HBGF8, anticorps HBNF, anticorps NEGF1, anticorps PTN-A, anticorps HB-GAM, anticorps HBBM, anticorps HBGF-8, anticorps OSF-1, anticorps HBBN, anticorps OSF, anticorps Osf-1, anticorps Osf1, anticorps Hbnf, anticorps pleiotrophin, anticorps pleiotrophin L homeolog, anticorps ptn, anticorps PTN, anticorps ptn.L, anticorps Ptn

Sujet: Pleiotrophin(PTN) also known as heparin-binding brain mitogen(HBBM) or heparin-binding growth factor 8(HBGF-8) or neurite growth-promoting factor 1(NEGF1) or heparin affinity regulatory peptide(HARP) or heparin binding growth associated molecule(HB-GAM) is a protein that in humans is encoded by the PTN gene. PTN is the first member of a family of developmentally regulated cytokines. The PTN gene is mapped to 7q33-q34. A mutant PTN that contained only the first N-terminal 40 amino acids was a dominant negative. Pleiotrophin is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. Pleiotrophin binds to cell-surface nucleolin as a low affinity receptor. This binding can inhibit HIV infection.

Synonyms: HARP antibody|HB-GAM antibody|HBBM antibody|HBGAM antibody|HBGF-8 antibody|HBGF8 antibody|HBNF antibody|HBNF-1 antibody|HBNF1 antibody|Heparin binding growth associated molecule antibody|Heparin binding growth factor 8 antibody|Heparin binding neurite outgrowth promoting factor 1 antibody|Heparin-binding brain mitogen antibody|Heparin-binding growth factor 8 antibody|Heparin-binding growth-associated molecule antibody|Heparin-binding neurite outgrowth-promoting factor 1 antibody|NEGF1 antibody|Neurite growth promoting factor 1 antibody|OSF-1 antibody|OSF1 antibody|Osteoblast-specific factor 1 antibody|Pleiotrophin antibody|PTN antibody|PTN_HUMAN antibody

UniProt: P21246

Pathways: Signalisation RTK