IGFBP3 anticorps (Middle Region)
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- Antigène Voir toutes IGFBP3 Anticorps
- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
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Épitope
- AA 182-198, Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IGFBP3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- Rabbit IgG polyclonal antibody for Insulin-like growth factor-binding protein 3(IGFBP3) detection. Tested with WB, IHC-P in Human.
- Séquence
- IKKGHAKDSQ RYKVDYE
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Insulin-like growth factor-binding protein 3(IGFBP3) detection. Tested with WB, IHC-P in Human.
Gene Name: insulin-like growth factor binding protein 3
Protein Name: Insulin-like growth factor-binding protein 3(IBP-3/IGF-binding protein 3/IGFBP-3) - Purification
- Immunogen affinity purified.
- Immunogène
- A synthetic peptide corresponding to a sequence in the middle region of human IGFBP-3(182-198aa IKKGHAKDSQRYKVDYE).
- Isotype
- IgG
- Top Product
- Discover our top product IGFBP3 Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Agent conservateur
- Thimerosal (Merthiolate), Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Date de péremption
- 12 months
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shRNA constructs targeting IGFBP-3 alleviate age related erectile dysfunction in the rat." dans: The Journal of urology, Vol. 192, Issue 3, pp. 990-6, (2014) (PubMed).
: "Higher expression of mRNA and protein of insulin-like growth factor binding protein-3 in old rat penile tissues: implications for erectile dysfunction." dans: The journal of sexual medicine, Vol. 8, Issue 8, pp. 2181-90, (2011) (PubMed).
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shRNA constructs targeting IGFBP-3 alleviate age related erectile dysfunction in the rat." dans: The Journal of urology, Vol. 192, Issue 3, pp. 990-6, (2014) (PubMed).
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- Antigène
- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
- Autre désignation
- IGFBP3 (IGFBP3 Produits)
- Synonymes
- anticorps BP-53, anticorps IBP3, anticorps AI649005, anticorps IGFBP-3, anticorps IGgfbp3, anticorps IGF-BP3, anticorps zgc:91788, anticorps IGFBP3, anticorps igfbp3, anticorps insulin like growth factor binding protein 3, anticorps insulin-like growth factor binding protein 3, anticorps IGFBP3, anticorps Igfbp3, anticorps igfbp3, anticorps IGFBP-3, anticorps LOC100305016
- Sujet
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IGFBP3, Insulin-like growth fator-binding protein 3, is a member of the insulin-like growth factor binding protein(IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. IGFBP3 is located on chromosome 7. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit(IGFALS) and either insulin-like growth factor(IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms: Acid stable subunit of the 140 K IGF complex antibody|Binding protein 29 antibody|Binding protein 53 antibody|BP 53 antibody|BP53 antibody|Growth hormone dependent binding protein antibody|IBP 3 antibody|IBP-3 antibody|IBP3 antibody|IBP3_HUMAN antibody|IGF binding protein 3 antibody|IGF-binding protein 3 antibody|IGFBP 3 antibody|IGFBP-3 antibody|IGFBP3 antibody|Insulin Like Growth Factor Binding Protein 3 antibody|Insulin-like growth factor-binding protein 3 antibody - UniProt
- P17936
- Pathways
- Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding
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