Sheep anti vesicle associated membrane protein 1 and 2, VAMP 1 and 2, VAMP1/2, VAMP 1/2, VAMP-1/2, Synaptobrevin 1 and 2,The MOC-1 antibody belongs to cluster 1 antibodies which react with neuroendocrine tissue (N-CAM) and in the lung typically detect SCLC and carcinoids. On the VI. International Workshop on Leukocyte Differentiation (Kobe 1996) this antibody has been designed as CD56, which is a known marker for natural killer cells (NK-cells). Lung cancer is a heterogeneous disease which may be characterized by five histopathological criteria. A distinction is drawn between squamous epithelial carcinoma, adenocarcinoma, large cell carcinoma, adenosquamous carcinoma and small cell lung carcinoma (SCLC). The first four in this line are cited as "non-SCLC" in literature. A number of antibodies have been used for the characterization and clustering of lung carcinoma during the 1. International Workshop on Small Cell Lung Cancer Antigens, London 1987. Cluster 1 membrane protein 125 - 145 kDa.
Immunogène
Preparation of a SCLC-derived cell line
Isotype
IgG
Indications d'application
Heat pre-treatment of formalin-fixed tissue with Unmasking Fluid C or G,IHC(P),60 min at RT,(RTU) neat
Restrictions
For Research Use only
Buffer
Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 30 immunohistochemical tests (100 μL working solution / test). Use appropriate antibody diluent if required.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
2-8°C
Antigène
VAMP1/VAMP2
(Vesicle-Associated Membrane Protein 1/2 (Synaptobrevin 1/2) (VAMP1/VAMP2))