NOLC1 anticorps

N° du produit ABIN306630

Détail du produit anti-NOLC1 anticorps

Antigène: NOLC1 (Nucleolar and Coiled-Body Phosphoprotein 1 (NOLC1))

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NOLC1 est non-conjugé

Application: Western Blotting (WB)

Clone: KAB40

Isotype: IgG1

Information d'application

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Détails sur NOLC1

Antigène: NOLC1 (Nucleolar and Coiled-Body Phosphoprotein 1 (NOLC1))

Autre désignation: p130 (NOLC1 Produits)

Sujet: The immunogen used was a GST fusion protein to the N terminus of p130. p130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107(collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors. This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130kDa. Synonyms: p130, Retinoblastoma-like protein 2, RBR-2, PRB2.

UniProt: Q08999

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling