AKAP12 anticorps

N° du produit ABIN306674

Détail du produit anti-AKAP12 anticorps

Antigène: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Reactivité: Rat

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP12 est non-conjugé

Application: Western Blotting (WB)

Isotype: IgG

Information d'application

Indications d'application: Antibody can be used for Western blot (2-5 ug/ml), immunohistochemistry and immunoprecipitation. Positive Control: Rat aortic smooth muscle.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/ml

Stock: -20 °C

Détails sur AKAP12

Antigène: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Autre désignation: SSeCKS - myristylated (PKC) substrate (AKAP12 Produits)

Synonymes: anticorps akap12, anticorps cb27, anticorps esr1, anticorps fb72g12, anticorps id:ibd1202, anticorps sb:cb27, anticorps si:ch73-192g21.1, anticorps wu:fb72g12, anticorps wu:fc21c03, anticorps AKAP12, anticorps AI317366, anticorps SSeCKS, anticorps Srcs5, anticorps Tsga12, anticorps AKAP12A, anticorps AKAP12B, anticorps AKAP12G, anticorps AKAP250, anticorps A kinase (PRKA) anchor protein 12b, anticorps A-kinase anchoring protein 12, anticorps A kinase (PRKA) anchor protein (gravin) 12, anticorps akap12b, anticorps AKAP12, anticorps Akap12

Sujet: Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation and proliferation, yet little is known about downstream substrates or their roles in normal or diseased states. SSeCKS, a novel protein kinase C substrate originally isolated as a src-suppressed negative mitogenic regulator in fibroblasts, controls actinbased cytoskeletal architecture and scaffolds key signaling kinases such as protein kinase C and protein kinase A. Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation. A role for SSeCKS, a PKA/PKC scaffolding protein, has been implicatedduring the process of spermiogenesis and in the actin-based stellate morphology of mesangial cellsSynonyms: SSeCKS, A-kinase anchor protein 12, AKAP12, src-suppressed C kinase substrate.

UniProt: Q62766

Pathways: cAMP Metabolic Process