SH3BP2 anticorps

N° du produit ABIN306729

Détail du produit anti-SH3BP2 anticorps

Antigène: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Reactivité: Souris

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3BP2 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris

Attributs du produit: Sh3bp2, SH3 domain-binding protein 2,3BP2 (SH3 binding protein 2) was identified as a protein binding to the SH3 domain of the Abl proto-oncogene. Murine 3BP2 cDNA encodes a 559 amino acid protein of 85 kDa consisting of an N-terminal PH domain, a C-terminal SH2 domain and intervening proline-rich sequences. 3BP2 interacts via its Sh2 domain with Syk family protein tyrosine kinases Syk, Zap70, Grb2, Cbl, PLC 1 and LAT in T lymphocytes and contributes to the transcriptional activation of NF-AT and AP-1. Mouse 3BP2 is 66 % homologous to the human protein at the amino acid level.

Purification: Ammonium Sulfate Precipitation

Immunogène: Antibody developed using SH2 domain of the 3BP2 protein fused to GST.

Isotype: IgG

Information d'application

Indications d'application: Detects 3BP2 protein by Western blot analysis. Detects a 85 kDa band in murine fibroblasts transfected with 3BP2. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur SH3BP2

Antigène: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Autre désignation: 3BP2 (SH3 Binding Protein 2) (SH3BP2 Produits)

Synonymes: anticorps SH3BP2, anticorps 3BP-2, anticorps 3BP2, anticorps CRBM, anticorps CRPM, anticorps SH3 domain binding protein 2, anticorps SH3-domain binding protein 2, anticorps SH3BP2, anticorps Sh3bp2

UniProt: Q06649

Pathways: TCR Signaling