VSX2 anticorps (N-Term)

N° du produit ABIN306799

Détail du produit anti-VSX2 anticorps

Antigène: VSX2 (Visual System Homeobox 2 (VSX2))

Épitope: N-Term

Reactivité: Humain

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp VSX2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: Human Chx10 protein

Réactivité croisée: Poulet, Humain, Souris, Rat

Attributs du produit: Ceh-10 homeodomain-containing homolog,Chx10 is a 46 kDa homeodomain protein of the paired-like class that is essential for development of the mammalian eye. Mutations in Chx10 cause microphthalmia, a cause of congenital blindness in humans, and the ocular retardation (or) phenotype in mice. In the developing mouse retina Chx10 is expressed in retinal progenitors, while in the mature retina, Chx10 expression becomes restricted to bipolar neurons. Concurrent with these expression patterns, the Chx10-/- (or) retina is thin due to a defect in proliferation of retinal progenitors, and lacks bipolar neurons. Chx10 is also expressed in the developing brainstem, thalamus, and spinal cord.

Immunogène: Antibody raised in sheep against a recombinant protein corresponding to amino acids 1 to 131 derived from the N-terminal region of the human Chx10 protein conjugated to KLH.

Isotype: IgG

Information d'application

Indications d'application: Detects Chx10 by Western blot at 0.5 to 1 μg/mL. Detects a 46 kDa band in mouse and rat retinal tissue lysates. Optimal concentration should be evaluated by serial dilutions. Suitable for use against recombinant proteins conjugated to OVA, GST, His tags and other.

Restrictions: For Research Use only

Stockage

Buffer: Ammonium sulphate precipitated antibody in PBS with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur VSX2

Antigène: VSX2 (Visual System Homeobox 2 (VSX2))

Autre désignation: chx 10 (NT) (VSX2 Produits)

UniProt: P58304

Pathways: Dopaminergic Neurogenesis