NPDC1 anticorps

N° du produit ABIN306963

Détail du produit anti-NPDC1 anticorps

Antigène: NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NPDC1 est non-conjugé

Application: Western Blotting (WB)

Specificité: Monoclonal Anti-NPDC-1 (mouse IgG1 isotype) is derived from the hybridoma 16E4 produced by immunizing mice with the peptide SLGSPVSSDPVHMS (Gene ID: 56654).

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: The discovery of NPDC-1 (neuronal proliferation, differentiation and control protein 1) was the result of a study of genes that were preferentially expressed in immortalized neural precursor cell lines at the onset of contact inhibition of proliferation and subsequent differentiation. It was further found that transfection of transformed cells with NPDC-1 led to increased doubling times and suppression of many characteristics of transformation. NPDC-1 is differentially expressed in brain and lung and has been shown to interact directly with the transcription factor E2F-1 as well as D-type cyclins and cdk2. NPDC-1 has been identified as a modulator of transcriptional events mediated by retinoic acid and the protein level and activity of NPDC-1 have been shown to be regulated by phosphorylation mediated proteasomal degradation.

Purification: Ion-exchange chromatography

Immunogène: Hybridoma produced by the fusion of splenocytes from mice immunized with a synthetic peptide SLGSPVSSDPVHMS derived from human NPDC-1 protein (Gene ID: 56654) and mouse myeloma cells.

Clone: 16E4

Isotype: IgG1

Information d'application

Indications d'application: Antibody can be used for Western blotting (1:1000 dilution). Optimal concentration should be evaluated by serial dilutions. Monoclonal Anti-NPDC-1 recognizes human NPDC-1 by immunoblotting (34-40 kDa).

Restrictions: For Research Use only

Stockage

Buffer: 20 mM sodium phosphate, 150 mM sodium chloride, 50 % glycerol, pH 7.5, 3 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur NPDC1

Antigène: NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))

Autre désignation: NPDC-1 (NPDC1 Produits)

Synonymes: anticorps AI314472, anticorps NPDC-1, anticorps CAB, anticorps CAB-, anticorps CAB-1, anticorps CAB1, anticorps neural proliferation, differentiation and control, 1, gene 1 L homeolog, anticorps neural proliferation, differentiation and control 1, anticorps neural proliferation, differentiation and control, 1, anticorps npdc1.1.L, anticorps Npdc1, anticorps NPDC1

UniProt: Q8WXX4