Hexokinase 1 anticorps (N-Term)

N° du produit ABIN317095

Détail du produit anti-Hexokinase 1 anticorps

Antigène: Hexokinase 1 (HK1)

Épitope: AA 1-917, N-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Hexokinase 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: The antibody recognizes all four isoforms of Hexokinase (1~4) in recombinant protein.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse (see pictures below).

Attributs du produit: Synonyms: HK1, Hexokinase type I, Brain form hexokinase

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogène: Recombinant Human Hexokinase 1 (1-917 aa) purified from E. coli

Clone: 4D7

Isotype: IgG2a

Information d'application

Indications d'application: ELISA. Western blot (1: 1,000). Immunofluorescence (1: 1,000). Immunohistochemistry on Paraffin Sections (5 μg/mL): This antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody, followed by alkalinephosphatase-streptavidin and chromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Hexokinase 1

Antigène: Hexokinase 1 (HK1)

Autre désignation: Hexokinase-1 (HK1 Produits)

Synonymes: anticorps HK1-ta, anticorps HK1-tb, anticorps HK1-tc, anticorps HKD, anticorps HKI, anticorps HMSNR, anticorps HXK1, anticorps Hexokinase, anticorps hk1, anticorps HEX, anticorps HEX-1, anticorps HK, anticorps ARABIDOPSIS THALIANA HEXOKINASE 1, anticorps ATHXK1, anticorps F19B15.160, anticorps F19B15_160, anticorps GIN2, anticorps GLUCOSE INSENSITIVE 2, anticorps HEXOKINASE, anticorps hexokinase 1, anticorps im:7148527, anticorps wu:fc09d08, anticorps wu:fc16e02, anticorps wu:fc21e02, anticorps wu:fq14b11, anticorps zgc:55790, anticorps zgc:77618, anticorps hexokinase-1, anticorps HK1, anticorps BB404130, anticorps Hk-1, anticorps Hk1-s, anticorps dea, anticorps mHk1-s, anticorps HEXOKIN, anticorps Hxk1, anticorps NtHxK1, anticorps NtHxk, anticorps hexokinase, anticorps StHK1, anticorps hxk, anticorps hk1-A, anticorps hexokinase 1, anticorps hexokinase-1, anticorps Hexokinase 1, anticorps hexokinase 1, putative, anticorps hexokinase 1 L homeolog, anticorps HK1, anticorps hk1, anticorps LOC100136279, anticorps Hex1, anticorps HXK1, anticorps Hk1, anticorps TA19800, anticorps hxk1, anticorps LOC107797523, anticorps LOC102604144, anticorps hk1.L

Sujet: Hexokinase is the first enzyme in the glycolytic pathway, catalyzing the transfer of a phosphoryl group from ATP to glucose to form glucose-6-phosphate and ADP. In mammals, four distinct enzymes-types 1 to 4 hexokinases-have been identified. The enzyme is found in most cells, but there is tissue specificity for the particular type of hexokinase. Hexokinase1 is found in the adipose tissue and liver and encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. A deficiency in hexokinase 1 is implicated in the rare hereditary autosomal recessive disease known as nonspherocytic haemolytic anaemia.Synonyms: Brain form hexokinase, HK1, Hexokinase type I

ID gène: 3098

UniProt: P19367

Pathways: Carbohydrate Homeostasis, L'effet Warburg