Glucagon Receptor anticorps
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- Antigène Voir toutes Glucagon Receptor (GCGR) Anticorps
- Glucagon Receptor (GCGR)
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Glucagon Receptor est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Specificité
- This antibody detects endogenous levels of Glucagon Receptor protein.(region surrounding Lys136)
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product GCGR Anticorps primaire
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- Indications d'application
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ELISA: 1/1000-1/10000. Western blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH ~7.2, 15 mM Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- Glucagon Receptor (GCGR)
- Autre désignation
- Glucagon Receptor (GCGR Produits)
- Synonymes
- anticorps GCGR, anticorps GGR, anticorps GR, anticorps glucagon receptor, anticorps GCGR, anticorps Gcgr
- Sujet
- Glucagon, a pancreatic hormone, functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior. Both glucagon and GLP-1 function through their specific binding to the glucagon receptor or GLP-1R, respectively. The glucagon receptor shows expression in liver, kidney and adipose tissue. The 56 GLP-1R expression primarily localizes to areas of the hypothalamus involved in feeding behavior. Both receptors and their ligands serve as potential targets for the therapeutic treatment of diabetes.Synonyms: GCGR, GL-R
- Poids moléculaire
- approx. 54 kDa
- ID gène
- 2642
- NCBI Accession
- NP_000151
- UniProt
- P47871
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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