LAMB2 anticorps

N° du produit ABIN317724

Détail du produit anti-LAMB2 anticorps

Antigène: LAMB2 (Laminin, beta 2 (Laminin S) (LAMB2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LAMB2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects endogenous levels of Laminin beta-2 protein. (region surrounding Cys91)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur LAMB2

Antigène: LAMB2 (Laminin, beta 2 (Laminin S) (LAMB2))

Autre désignation: Laminin beta-2 (LAMB2 Produits)

Synonymes: anticorps LAMS, anticorps NPHS5, anticorps AW211941, anticorps Lamb-2, anticorps Lams, anticorps SLAM, anticorps lamb1, anticorps lams, anticorps LAMC1, anticorps laminin, anticorps laminin subunit beta 2, anticorps laminin, beta 2, anticorps laminin subunit beta 2 L homeolog, anticorps laminin, beta 2 (laminin S), anticorps LAMB2, anticorps Lamb2, anticorps lamb2.L

Sujet: The Laminins comprise a growing family of disulfide-linked heterotrimers consisting of three genetically distinct polypeptide chains, designated alpha, beta and gamma. A major component of the basal lamina, Laminins play a crucial role in providing a scaffolding upon which tissues are assembled and which serves as a physical barrier separating specialized tissues. During embryogenesis and early development, cells migrate along basement membranes, which are required for the polarization of cells. The beta-2 laminin chain plays a role in melanoma spread, promoting tumor migration along the abluminal surface of vessel, a phenomenon which has been termed extra-vascular migratory metastasis.Synonyms: LAMB2, LAMS, Laminin B1s chain, Laminin-11 subunit beta, Laminin-14 subunit beta, Laminin-15 subunit beta, Laminin-3 subunit beta, Laminin-4 subunit beta, Laminin-7 subunit beta, Laminin-9 subunit beta, S-laminin

Poids moléculaire: approx. 210 kDa

ID gène: 3913

NCBI Accession: NP_002283

UniProt: P55268

Pathways: Skeletal Muscle Fiber Development