ALDOB anticorps

N° du produit ABIN317837

Détail du produit anti-ALDOB anticorps

Antigène: ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALDOB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects endogenous levels of Aldolase B protein.(region surrounding Trp148)

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-ALDOB (ABIN317837)

Walmsley, Freund, Curthoys: "Proteomic profiling of the effect of metabolic acidosis on the apical membrane of the proximal convoluted tubule." dans: American journal of physiology. Renal physiology, Vol. 302, Issue 11, pp. F1465-77, (2012) (PubMed).

Détails sur ALDOB

Antigène: ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))

Autre désignation: Aldolase B / ALDOB (ALDOB Produits)

Synonymes: anticorps aldb, anticorps aldo2, anticorps xaldb, anticorps ALDOB, anticorps aldob, anticorps ALDB, anticorps ALDO2, anticorps Aldo-2, anticorps Aldo2, anticorps BC016435, anticorps LIV10, anticorps fb25f09, anticorps wu:fb25f09, anticorps aldolase B, anticorps aldolase, fructose-bisphosphate B, anticorps aldolase, fructose-bisphosphate B S homeolog, anticorps aldolase b, fructose-bisphosphate, anticorps aldolase B, fructose-bisphosphate, anticorps xaldb, anticorps aldob, anticorps aldob.S, anticorps ALDOB, anticorps Aldob

Sujet: Fructose 1,6-bisphosphate Aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1,6-bisphosphate.Fructose 1,6-bisphosphate Aldolase exists as three forms, the muscle-specific Aldolase A, the liver-specific Aldolase B, and the brain-specific Aldolase C. Aldolase A, B, and C arose from a common ancestral gene, from which Aldolase B first diverged. Aldolase A is one of the most highly conserved enzymes known, with only about 2 % of the residues changing per 100 million years. Aldolase B is regulated by the hormones insulin and glucagons and has been implicated in hereditary fructose intolerance disease. Aldolase C is 36 kDa polypeptide that is exclusively expressed in Purkinje cells. Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase C-negative Purkinje cells.Synonyms: Fructose-bisphosphate aldolase B, Liver-type aldolase

Poids moléculaire: approx. 45 kDa

ID gène: 229

NCBI Accession: NP_000026

UniProt: P05062