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REM1 anticorps

REM1 Reactivité: Humain, Souris, Rat WB, IF, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN317842
  • Antigène Voir toutes REM1 Anticorps
    REM1 (RAS (RAD and GEM)-Like GTP-Binding 1 (REM1))
    Reactivité
    • 18
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 29
    • 4
    Lapin
    Clonalité
    • 31
    • 2
    Polyclonal
    Conjugué
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp REM1 est non-conjugé
    Application
    • 21
    • 13
    • 13
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects endogenous levels of Rad GTPase protein.(region surrounding Leu80)
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product REM1 Anticorps primaire
  • Indications d'application
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    REM1 (RAS (RAD and GEM)-Like GTP-Binding 1 (REM1))
    Autre désignation
    REM1 (REM1 Produits)
    Synonymes
    anticorps GD:REM, anticorps GES, anticorps E030011C07Rik, anticorps Rem, anticorps GEM, anticorps SI:zK76P14.3, anticorps horizin, anticorps rem, anticorps zgc:56144, anticorps RRAD and GEM like GTPase 1, anticorps rad and gem related GTP binding protein 1, anticorps RAS (RAD and GEM)-like GTP-binding 1, anticorps REM1, anticorps Rem1, anticorps rem1
    Sujet
    The Ras-encoded family of proteins bind GDP and GTP with high affinity. They possess a low level of intrinsic GTPase activity that increases more than 100-fold when interacting with cytosolic GTPase activating protein (GAP). Ras family members include H-Ras, K-Ras, N-Ras, M-Ras, R-Ras, ERas, Rheb, TC 21, RASL11B and Rad (Ras associated with diabetes) GTPase.Rad GTPase is a GTP-binding protein that is similar to Ras but has unique features. Unlike other small GTPases, Rad GTPase lacks typical pren-ylation motifs at its C terminus. The Rad GTPase enzyme binds calmodulin, inhibits vascular lesion formation, has low intrinsic GTPase activity and cannot be stimulated by any known GAP molecules. Rad GTPase is expressed in skeletal muscle, cardiac muscle and lung tissues and is overexpressed in the skeletal muscle tissue of individuals with type II diabetes.Synonyms: GES, GTP-binding protein REM 1, GTPase-regulating endothelial cell sprouting, REM, Rad and Gem-like GTP-binding protein 1
    Poids moléculaire
    approx. 33 kDa
    ID gène
    28954
    NCBI Accession
    NP_054731
    UniProt
    O75628
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