NHE7 anticorps
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- Antigène Voir toutes NHE7 (SLC9A7) Anticorps
- NHE7 (SLC9A7) (Sodium Hydrogen Exchanger 7 (SLC9A7))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NHE7 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- NHE-7 antibody detects endogenous levels of NHE-7 protein.(region surrounding Asp566)
- Purification
- Affinity chromatography
- Top Product
- Discover our top product SLC9A7 Anticorps primaire
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- Indications d'application
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- NHE7 (SLC9A7) (Sodium Hydrogen Exchanger 7 (SLC9A7))
- Autre désignation
- SLC9A7 / NHE7 (SLC9A7 Produits)
- Synonymes
- anticorps NHE7, anticorps wu:fk03b09, anticorps zgc:101088, anticorps zgc:113878, anticorps A530087D17Rik, anticorps NHE-7, anticorps SLC9A6, anticorps Nhe7, anticorps solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7, anticorps solute carrier family 9 (sodium/hydrogen exchanger), member 7, anticorps solute carrier family 9 member A7, anticorps slc9a7, anticorps Slc9a7, anticorps SLC9A7
- Sujet
- Na+/H+ exchangers (NHE) of mammalian cells are plasma membrane intrinsic proteins mediating exchange of N+ and H+ ions in various tissues. The NHE catalyzes the electroneural transport of extracellular Na+ for intracellular H+. They play a major role in regulation of intracellular pH ( pH i) in addition to trans-cellular absorption of Na+, cell volume regulation and possibly in cell proliferation. These primary functions of the Na+/H+ exchanger have been related to many pathophysiological states, include hypertension, organ growth and hypertrophy, regression of cancer and renal intestinal disorders. At least 7 NHE isoforms (NHE1-7) have been cloned so far. They are all similar in their primary structure and predicted to have 10-12 transmembrane domains. The C-terminal domain of NHEs are predicted to be intracellular. NHE7 (human 725 aa, chromosome Xp11.4) is ubiquitously expressed, and predominantly localizes to the trans-golgi network. NHE7 mediates the influx of Na+ or K+ in exchange for H+. It is ~70 % related to NHE6 but relatively less (~25 %) homologous with other NHEs.Synonyms: NHE-7, Na(+)/H(+) exchanger 7, Sodium/hydrogen exchanger 7, Solute carrier family 9 member 7
- Poids moléculaire
- approx. 80 kDa
- ID gène
- 84679
- NCBI Accession
- NP_115980
- UniProt
- Q96T83
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