Tetanus Toxin anticorps

N° du produit ABIN318666

Détail du produit anti-Tetanus Toxin anticorps

Antigène: Tetanus Toxin (TetX)

Reactivité: Clostridium tetani

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Tetanus Toxin est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects the tetanus toxin which is produced by the soil micro-organism Clostridium tetani. C. tetani infection results in its systemic growth and secretion of tetanus, which causes muscle spasms by inhibiting neurotransmitter release. The antibody also reacts with the C-fragment of tetanus toxin.

Purification: Affinity Chromatography.

Immunogène: Tetanus Exotoxin

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1g/mL. Western Blot: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 5.0 mg/mL

Buffer: PBS pH 7.2 containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Tetanus Toxin

Antigène: Tetanus Toxin (TetX)

Autre désignation: Tetanus Toxin (TetX Produits)

Classe de substances: Bacteria

Sujet: Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.Synonyms: Clostridium tetani toxin, tetX

ID gène: 1061100

NCBI Accession: NP_783831

UniProt: P04958