BAG1 anticorps (C-Term)
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- Antigène Voir toutes BAG1 Anticorps
- BAG1 (BCL2-Associated Athanogene (BAG1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BAG1 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody detects an epitope within the C-terminal (CT) region of Bcl-2 associated athanogene-1 (BAG1).
- Purification
- Purified
- Immunogène
- 14 amino acid peptide from near the carboxy terminus of human BAG1.
- Isotype
- IgG
- Top Product
- Discover our top product BAG1 Anticorps primaire
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- Indications d'application
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Western Blot: 1 - 2g/mL, detects a band of approximately 39 kDa in PC3 cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0mg/mL
- Buffer
- Phosphate buffered saline containing 0.02 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- BAG1 (BCL2-Associated Athanogene (BAG1))
- Autre désignation
- BAG1 (BAG1 Produits)
- Synonymes
- anticorps BAG-1, anticorps HAP, anticorps RAP46, anticorps Rap46, anticorps Bag-1, anticorps ATBAG1, anticorps BCL-2-associated athanogene 1, anticorps MSG15.15, anticorps MSG15_15, anticorps im:7148830, anticorps si:dkey-216e9.4, anticorps BCL2 associated athanogene 1, anticorps putative bcl2-associated athanogene, anticorps BCL2-associated athanogene 1, anticorps Bcl2 associated athanogene 1, anticorps BAG family molecular chaperone regulator 1, anticorps BCL-2-associated athanogene 1, anticorps BAG1, anticorps Smp_005900, anticorps Bag1, anticorps bag-1, anticorps LOC781741, anticorps bag1
- Sujet
- BAG1 is a co-chaperone protein which binds to and regulates the 70kD heat shock proteins (Hsp70/Hsc70). BAG1 has also been shown to interact with the kinase Raf1, a number of steroid and tyrosine kinase receptors, and the Bcl-2 family of proteins. It is thought to function as a molecular switch between cell growth and differentiation, and cell survival. The BAG1 gene encodes three different isoforms, a predominantly cytosolic form of 36kD (BAG1S), a 46kD cytosolic and nuclear form (BAG1M), and a predominantly nuclear form 50kD (BAG1L). BAG1 displays potent neuroprotective activity in vivo against stroke, and could be used for reducing brain injury during cerebral ischemia and neurodegenerative diseases. BAG1 may also promote chemoresistance, growth factor independence, and anchorage independent cell growth in tumour cells.Synonyms: BAG family molecular chaperone regulator 1, BAG-1, Bcl-2-associated athanogene 1, Glucocorticoid receptor-associated protein RAP46, HAP, RAP46
- ID gène
- 573
- NCBI Accession
- NP_001165886
- UniProt
- Q99933
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