TLR1 anticorps (N-Term)

N° du produit ABIN318756

Cet anticorps anti-TLR1 Polyclonal Lapin (ABIN318756) détecte spécifiquement TLR1 dans WB et IHC (fro). L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour TLR1 anticorps (N-Term) (ABIN318756)

Antigène: TLR1 (Toll-Like Receptor 1 (TLR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-TLR1 anticorps

Épitope: N-Term

Purification: Affinity Chromatography

Immunogène: A 16 amino acid peptide located near the amino terminus of Human CD281

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry on frozen sections: 10g/mL. Western Blot: 1 - 4g/mL, detects a band of approximately 90 kDa in mouse spleen lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur TLR1

Antigène: TLR1 (Toll-Like Receptor 1 (TLR1))

Autre désignation: CD281 / TLR1

Sujet: TLRs recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and serve as an important link between the innate and adaptive immune response through the production of cytokines. TLR1 is co-expressed with TLR2 on monocytes and dendritic cells where they form heterodimers that can recognize peptidoglycan and bacterial lipopeptides, and in particular triacylated lipoproteins. TLR1 can also regulate other TLR responses, TLR1 can associate with TLR4 and inhibit its signalling in endothelial cells, and can associate with TLR2 to inhibit the TLR2/TLR6 mediated response to phenol-soluble modulin.Synonyms: KIAA0012, TIL, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein

ID gène: 9606

UniProt: Q15399

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades