ELISA: 1: 40000 - 1: 160000. ,Western Blot: 1: 1000 - 1: 5000, detects a bands of approximately 100 and 50 kDacorresponding to iASPP isoforms 1 and 2 respectively. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
anticorps AV260376, anticorps IASPP, anticorps Nkip1, anticorps wa3, anticorps zgc:113058, anticorps NKIP1, anticorps RAI, anticorps RAI4, anticorps protein phosphatase 1, regulatory (inhibitor) subunit 13 like, anticorps protein phosphatase 1, regulatory subunit 13 like, anticorps protein phosphatase 1 regulatory subunit 13 like, anticorps protein phosphatase 1 regulatory subunit 13 like L homeolog, anticorps Ppp1r13l, anticorps ppp1r13l, anticorps PPP1R13L, anticorps ppp1r13l.L
Sujet
IASPP plays a central role in regulation of apoptosis and transcription via its interaction with NFkB and p53 proteins. At present, the iASPP gene is thought to encode three isoforms, isoform 1 is predominantly located in the cytoplasm, whilst isoforms 2 and 3 are nuclear proteins. iASPP is highly expressed in the heart, placenta and prostate. iASPP has been shown to have oncogenic properties in human breast carcinomas.Synonyms: IASPP, Inhibitor of ASPP protein, NFkB-interacting protein 1, NKIP1, PPP1R13B-like protein, PPP1R13BL, RAI, RelA-associated inhibitor