PTK7 anticorps (N-Term)
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- Antigène Voir toutes PTK7 Anticorps
- PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PTK7 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody recognises Protein tyrosine kinase-like 7 (PTK7).
- Purification
- Antisera to human PTK7 (NT) were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
- Immunogène
- A 15 amino acid peptide located near the N-terminal region of human PTK7.
- Isotype
- IgG
- Top Product
- Discover our top product PTK7 Anticorps primaire
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- Indications d'application
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Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 86 kDa in colon tissuelysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline containing 0.02 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
- Autre désignation
- PTK7 / CCK4 (PTK7 Produits)
- Synonymes
- anticorps PTK7, anticorps CCK-4, anticorps CCK4, anticorps Srf, anticorps 8430404F20Rik, anticorps chz, anticorps mPTK7/CCK4, anticorps KLG, anticorps protein tyrosine kinase 7 (inactive), anticorps protein tyrosine kinase 7, anticorps PTK7 protein tyrosine kinase 7, anticorps PTK7, anticorps Ptk7
- Sujet
- PTK7 is a member of the receptor tyrosine kinase family, otherwise known as Colon Carcinoma Kinase 4 (CCK4). PTK7 is highly expressed in the kidney, liver, lung, pancreas and melanocytes with weaker expression being detected in the thyroid gland, ovaries, brain, heart and skeletal muscle. PTK7 may play a role in embryonic development. It is thought to function as a cell adhesion molecule and as a novel regulator of the planar cell polarity (PCP) pathway in vertebrates. Studies also suggest that PTK7 may be involved in the tumour progression. A loss of PTK7 expression has been observed in melanoma cell lines, whereas increased levels of PTK7 have been detected in high-throughput acute myeloid leukaemia samples. In addition, PTK7 is not expressed in normal colon but has been detected in colon carcinomas and as such is a potential marker for tumour progression.Synonyms: CCK-4, Colon carcinoma kinase 4, Tyrosine-protein kinase-like 7
- ID gène
- 5754
- NCBI Accession
- NP_002812
- UniProt
- Q13308
- Pathways
- Signalisation RTK, Tube Formation
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