CX3CR1 anticorps (AA 175-189)

N° du produit ABIN319015

Détail du produit anti-CX3CR1 anticorps

Antigène: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Épitope: AA 175-189

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CX3CR1 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody recognises CX3CR1, a seven transmembrane protein recently identified as a receptor for fractalkine. CX3CR1 is expressed in a variety of human tissues and mediates leucocyte adhesion and migration.

Purification: Purified

Immunogène: Peptide corresponding to amino acids 175 to 189 of human CX3CR1.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1: 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline containing 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CX3CR1

Antigène: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Autre désignation: CX3CR1 / GPR13 (CX3CR1 Produits)

Synonymes: anticorps CCRL1, anticorps CMKBRL1, anticorps CMKDR1, anticorps GPR13, anticorps GPRV28, anticorps V28, anticorps Rbs11, anticorps C-X3-C motif chemokine receptor 1, anticorps chemokine (C-X3-C motif) receptor 1, anticorps CX3C chemokine receptor 1, anticorps CX3CR1, anticorps Cx3cr1, anticorps LOC100559882

Sujet: CX3CR1 is one of the chemokine receptors that are required as co-receptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion and has been implicated in tumor metastasis. CX3CR1 is expressed in a variety of human tissues and cell lines.Synonyms: Beta chemokine receptor-like 1, C-X3-C CKR-1, CMK-BRL-1, CMKBRL1, CX3C chemokine receptor 1, Fractalkine receptor, G-protein coupled receptor 13, V28

ID gène: 1524

NCBI Accession: NP_001328

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin