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KDM5A anticorps (AA 1416-1434)

KDM5A Reactivité: Humain WB, IF, FACS Hôte: Souris Monoclonal 18E8 unconjugated
N° du produit ABIN3201015
  • Antigène Voir toutes KDM5A Anticorps
    KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
    Épitope
    • 15
    • 9
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 1416-1434
    Reactivité
    • 67
    • 15
    • 4
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 62
    • 4
    Souris
    Clonalité
    • 55
    • 12
    Monoclonal
    Conjugué
    • 25
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KDM5A est non-conjugé
    Application
    • 46
    • 25
    • 17
    • 14
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    Specificité
    Specific to human and mouse RBP2. Can detect endogenous levels of RBP2.
    Purification
    Purified
    Stérilité
    Sterile filtered
    Immunogène
    A synthetic peptide corresponding to human RBP2, aa 1416-1434.
    Clone
    18E8
    Isotype
    IgG2a kappa
  • Indications d'application
    1. Western blotting: ~1 g/mL
    2. Immunofluorescence staining
    3. Flow Cytometry: 1 g for 10^6 cells
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol
    Agent conservateur
    Azide free
    Stock
    -20 °C
  • Lopez-Bigas, Kisiel, Dewaal, Holmes, Volkert, Gupta, Love, Murray, Young, Benevolenskaya: "Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation." dans: Molecular cell, Vol. 31, Issue 4, pp. 520-30, (2008) (PubMed).

    Christensen, Agger, Cloos, Pasini, Rose, Sennels, Rappsilber, Hansen, Salcini, Helin: "RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3." dans: Cell, Vol. 128, Issue 6, pp. 1063-76, (2007) (PubMed).

    Klose, Yan, Tothova, Yamane, Erdjument-Bromage, Tempst, Gilliland, Zhang, Kaelin: "The retinoblastoma binding protein RBP2 is an H3K4 demethylase." dans: Cell, Vol. 128, Issue 5, pp. 889-900, (2007) (PubMed).

  • Antigène
    KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
    Autre désignation
    KDM5A (KDM5A Produits)
    Synonymes
    anticorps Jarid1a, anticorps JARID1A, anticorps RBBP-2, anticorps RBBP2, anticorps RBP2, anticorps AA409370, anticorps C76986, anticorps Rbbp2, anticorps lysine demethylase 5A, anticorps lysine (K)-specific demethylase 5A, anticorps Kdm5a, anticorps KDM5A
    Sujet
    RBP2 was originally identified as a retinoblastoma binding protein. It is also known as JARID1A (Jumonji, AT rich interactive domain 1A). RBP2 plays both negative and positive roles in RB- mediated transcriptional activation, depending on the kinds of genes and regulates differentiation by its function as an H3K4 histone demethylase.
    UniProt
    P29375
    Pathways
    Chromatin Binding, L'effet Warburg
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