EID1
Reactivité: Humain
ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
1) Western blotting: ~1 g/mL 2) Immunofluorescence staining: 1~5 g/mL 3) ELISA Other applications have not been tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS ( pH 7.4), 50 % glycerol. Azide- and carrier-free
Agent conservateur
Azide free
Stock
-20 °C
Stockage commentaire
Upon arrival centrifuge briefly and store at -20 C.
Nguyen, Baglia, Huang, Baker, McCance: "Acetylation regulates the differentiation-specific functions of the retinoblastoma protein." dans: The EMBO journal, Vol. 23, Issue 7, pp. 1609-18, (2004) (PubMed).
MacLellan, Xiao, Abdellatif, Schneider: "A novel Rb- and p300-binding protein inhibits transactivation by MyoD." dans: Molecular and cellular biology, Vol. 20, Issue 23, pp. 8903-15, (2000) (PubMed).
Antigène
EID1
(EP300 Interacting Inhibitor of Differentiation 1 (EID1))
EID1 (EP300 interacting inhibitor of differentiation 1) encodes a 21 kDa protein, which interacts with RB1 and EP300 and acts as a repressor of MYOD1 transcription. EID1 inhibits EP300 and CBP histone acetyltransferase activity. It may be involved in coupling cell cycle exit to the transcription of genes required for cellular differentiation.