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CHEK1 anticorps
CHEK1
Reactivité: Humain, Souris
WB, ELISA
Hôte: Souris
Monoclonal
2G1D5
unconjugated
N° du produit ABIN3209997
Détail du produit anti-CHEK1 anticorps
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Antigène
Voir toutes CHEK1 Anticorps
CHEK1
(Checkpoint Kinase 1 (CHEK1))
Reactivité
Toutes les réactivités sur CHEK1 Anticorps
Humain, Souris
Hôte
Toutes les hôtes sur CHEK1 Anticorps
Souris
Clonalité
Toutes les clonalités sur CHEK1 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers CHEK1 Anticorps
Cet anticorp CHEK1 est non-conjugé
Application
Tous les applications à travers CHEK1 Anticorps.
Western Blotting (WB), ELISA
Réactivité croisée
Souris
Purification
Purified antibody.
Immunogène
CHK1 antibody was raised in Mouse using a purified recombinant fragment of CHK1 expressed in E. coli as the immunogen.
Clone
2G1D5
Isotype
IgG1
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Information d'application
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Indications d'application
ELISA: 1:10,000, WB: 1:500-1:2,000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
Lot specific
Buffer
Purified antibody supplied in PBS containing 0.03 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Détails sur CHEK1
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Antigène
CHEK1
(Checkpoint Kinase 1 (CHEK1))
Autre désignation
CHK1 (CHEK1 Produits )
Synonymes
anticorps An08g10320, anticorps AO090003000441, anticorps CHK1, anticorps chk1, anticorps C85740, anticorps Chk1, anticorps rad27, anticorps id:ibd2720, anticorps zgc:56093, anticorps CHEK1, anticorps checkpoint kinase 1, anticorps serine/threonine-protein kinase chk1, anticorps serine/threonine-protein kinase Chk1, anticorps CAMK/CAMKL/CHK1 protein kinase Chk1, anticorps checkpoint kinase 1 S homeolog, anticorps CHEK1, anticorps ANI_1_2436074, anticorps AOR_1_768154, anticorps PTRG_04183, anticorps SJAG_01680, anticorps PAAG_04978, anticorps MCYG_03290, anticorps VDBG_03742, anticorps chek1.S, anticorps Chek1, anticorps chek1
Sujet
CHK1 is a kinase that phosphorylates Cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm. Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1. Consequently, a cell is prevented from entering mitosis. Synonyms: Monoclonal CHK1 antibody, Anti-CHK1 antibody, CHK-1 antibody, CHK 1 antibody, CHEK1 antibody.
Pathways
Signalisation p53 , Apoptose , Cycle Cellulaire , Réparation de l'ADN
Vus récemment
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