SERPINA1 anticorps

N° du produit ABIN336976

Détail du produit anti-SERPINA1 anticorps

Antigène: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SERPINA1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Molecular Weight: 51 kDa.

Immunogène: Purified human ATT

Information d'application

Indications d'application: IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections, cell smears) 1:50-1:200 using streptavidin-Biotin system or polymer system. Prediluted antibody is used directly without dilution. FFPE tissue sections require antigen retriever (boiling tissue in 10 mM citrate pH 6.0 for 10-20 minutes, followed by cooling at RT for 15-20 minutes). The optimum dilution should be determined by the individual lab. Positive Control: Human tonsil, liver. Cellular Localization: Cytoplasmic staining of macrophages.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is supplied with 1% BSA in PBS with 0.05% azide, pH 7.4. The Prediluted antibody is supplied in our Universal antibody dilution buffer (AR-6526) green in color.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur SERPINA1

Antigène: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Autre désignation: a-1 Antitrypsin (SERPINA1 Produits)

Synonymes: anticorps AACT, anticorps ACT, anticorps GIG25, anticorps A1AT, anticorps PI, anticorps alpha-1-PI, anticorps A1A, anticorps AAT, anticorps PI1, anticorps PRO2275, anticorps alpha1AT, anticorps Pi, anticorps Spi1, anticorps MGC64429, anticorps serpina1d, anticorps Aps, anticorps SERPINA3-5, anticorps serpin family A member 3, anticorps alpha-1-antiproteinase F precursor, anticorps serpin family A member 1, anticorps alpha-1-antitrypsin, anticorps calumenin, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 S homeolog, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5, anticorps SH2B adaptor protein 2, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog, anticorps SERPINA3, anticorps LOC100008973, anticorps SERPINA1, anticorps LOC100328621, anticorps CALU, anticorps Serpina1, anticorps serpina1.S, anticorps serpina1, anticorps SPIA5, anticorps Sh2b2, anticorps Calu, anticorps serpina1.L

Sujet: Alpha-1-Antitrypsin (AAT) is a 51 kDa glycoprotein synthesized in the liver. It is a serum protease inhibitor in neutrophil elastase, collagenase and chymotrypsin. This protein is a serum trypsin inhibitor, the correct name is alpha-1-proteinase inhibitor (A1PI). Disorders of this enzyme include, deficiency, in a hereditary disorder, this causes degradation of lung tissue and causes pulmonary emphysema, it also causes chronic liver disease and hepatocarcinoma. AAT is present in normal liver cells, histocytes, monocytes and a variety of epithelial and mesenchymal tumors. Increase in serum levels of AAT is also reported in rheumatoid arthritis, bacterial infection, vasculistis and carcinomatosis. Intended USE: Immunohistochemistry (IHC) and Immunocytchemistry (ICC)