CD35 anticorps
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- Antigène Voir toutes CD35 (CR1) Anticorps
- CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
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Reactivité
- Humain, Babouin, Cynomolgus, Macaque rhésus
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD35 est non-conjugé
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Marque
- IHC-plus™
- Specificité
- Is a single chain cell surface glycoprotein which exists in four allotypic forms (A, B, C, D) of 190kD, 220kD, 160kD and 250kD respectively. The molecule is expressed by granulocytes, monocytes, B cells and some T cells. Functionally CD35 acts as a receptor for the C3b component of complement. Clone E11 has been reported to be suitable for use in Western Blot.
- Purification
- Protein A purified
- Immunogène
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Human acute monocytic leukaemia cells.
Type of Immunogen: Cells - Clone
- E11
- Isotype
- IgG1
- Top Product
- Discover our top product CR1 Anticorps primaire
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- Indications d'application
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Approved: Flo (1:50 - 1:100), IHC, IHC-Fr, IHC-P (10 μg/mL), WB
Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL. Flow Cytometry: Use 10 μL of the diluted antibody to label 10^6 cells or 100 μL whole blood. Histology Positive Control Tissue: Tonsil. - Commentaires
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4. Sourced in TCS.
- Agent conservateur
- Azide free
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Antigène
- CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
- Autre désignation
- CR1 / CD35 (CR1 Produits)
- Sujet
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Name/Gene ID: CR1
Subfamily: Serine S1
Family: Protease
Synonyms: CR1, C3b/C4b receptor, C3-binding protein, CD35, C3BR, Knops blood group antigen, C4BR, CD35 antigen, Complement receptor type 1, KN - ID gène
- 1378
- UniProt
- P17927
- Pathways
- Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
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